SynthesisNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2021
COVID-19, de novo seizures, and epilepsy: a systematic review.
Synthesis in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.
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Who cites it
48 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Late neurological consequences of SARS-CoV-2 infection: New challenges for the neurologist.Frontiers in neuroscience · 2023Pooled it
- Global, regional, and national burden of epilepsy, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021.The Lancet. Public health · 2025Article
- Systematic review and meta-analysis of brain neuroimaging abnormalities in COVID-19 patients and survivors.Psychoradiology · 2025Article
- Investigating the Relationship of Age and Gender with the Prevalence of Seizure Types in Children with COVID-19: An Analytical Cross-Sectional Study in Firouzabadi Hospital.Iranian journal of child neurology · 2025Article
- Article
- Clinical outcomes of patients with seizure admitted for COVID-19: Findings from the Philippine CORONA study.Heliyon · 2024Article
- Complications of COVID-19 on the Central Nervous System: Mechanisms and Potential Treatment for Easing Long COVID.Aging and disease · 2023Review
- COVID-19 in Children with West Syndrome: An Ambispective Study.Indian journal of pediatrics · 2023Article
- Impact of COVID-19 Infection in West Syndrome: The Need for More Data.Indian journal of pediatrics · 2023Article
- Potential use of renin-angiotensin-aldosterone system inhibitors to reduce COVID-19 severity.Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology · 2023Review
- Strategies for the Emergency Treatment of Pregnant Women with Neurological Symptoms during the COVID-19 Pandemic.Aging and disease · 2023Article
- Incidence of Epilepsy and Seizures Over the First 6 Months After a COVID-19 Diagnosis: A Retrospective Cohort Study.Neurology · 2023Article
- SARS-CoV-2 infection and multi-organ system damage: A review.Biomolecules & biomedicine · 2023Review
- Potential risk of liver injury in epileptic patients during COVID-19 pandemic.World journal of virology · 2022Review
- Effect of the COVID-19 Pandemic on Seizure Control Status in Patients with Epilepsy.Iranian journal of medical sciences · 2022Article
- Review
- Review
- Intravenous Brivaracetam in the Management of Acute Seizures in the Hospital Setting: A Scoping Review.Journal of intensive care medicine · 2022Article
- Observational retrospective analysis of vaccination against SARS-CoV-2 and seizures: VACCI-COVID registry.Epilepsy & behavior : E&B · 2022Observational
- Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
objectiveWe discuss the evidence on the occurrence of de novo seizures in patients with COVID-19, the consequences of this catastrophic disease in people with epilepsy (PWE), and the electroencephalographic (EEG) findings in patients with COVID-19.
methodsThis systematic review was prepared according to the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. MEDLINE, Scopus, and Embase from inception to August 15, 2020 were systematically searched. These key words were used: "COVID" AND "seizure" OR "epilepsy" OR "EEG" OR "status epilepticus" OR "electroencephalography".
resultsWe could identify 62 related manuscripts. Many studies were case reports or case series of patients with COVID-19 and seizures. PWE showed more psychological distress than healthy controls. Many cases with new-onset focal seizures, serial seizures, and status epilepticus have been reported in the literature. EEG studies have been significantly ignored and underused globally.
conclusionMany PWE perceived significant disruption in the quality of care to them, and some people reported increase in their seizure frequency since the onset of the pandemic. Telemedicine is a helpful technology that may improve access to the needed care for PWE in these difficult times. De novo seizures may occur in people with COVID-19 and they may happen in a variety of forms. In addition to prolonged EEG monitoring, performing a through metabolic investigation, electrocardiogram, brain imaging, and a careful review of all medications are necessary steps. The susceptibility of PWE to contracting COVID-19 should be investigated further.
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