Evidence map›Paper›PMID 33237477›Full record

ReviewCell and tissue research2021

Olfactory signaling via trace amine-associated receptors.

Adam Dewan

Open access · greenAbstract readReview
In one paragraph

Review in Cell and tissue research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 40 citations in OpenAlex.

  1. Review
  2. Article
  3. The Role of Olfaction in Dogs: Evolution, Biology, and Human-Oriented Work.Animals : an open access journal from MDPI · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Deorphanization of Olfactory Trace Amine-Associated Receptors.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Molecular Basis of Human Trace Amine-Associated Receptor 1 Activation.bioRxiv : the preprint server for biology · 2023
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Adam DewanDepartment of Psychology, Florida State University, 1107 W. Call St, Tallahassee, FL, 32306, USA. dewan@psy.fsu.edu.ORCID http://orcid.org/0000-0003-1627-5730
Florida State University · US

Funding

Glomerular domains and olfactory circuitryR03DC014565 · NIDCD · NORTHWESTERN UNIVERSITY · PI DEWAN, ADAM KABIR · 2016 to 2018
$462k
NIDCD NIH HHS DC014565NIDCD NIH HHS R03 DC014565
6 · The paper itself

Abstract

Trace amine-associated receptors (TAARs) are a family of G protein-coupled receptors that function as odorant receptors in the main olfactory system of vertebrates. TAARs are monoallelically expressed in primary sensory neurons where they couple to the same transduction cascade as canonical olfactory receptors and are mapped onto glomeruli within a specific region of the olfactory bulb. TAARs have a high affinity for volatile amines, a class of chemicals that are generated during the decomposition of proteins and are ubiquitous physiological metabolites that are found in body fluids. Thus, amines are proposed to play an important role in intra- and interspecific communication such as signaling the sex of the conspecific, the quality of the food source, or even the proximity of a predator. TAARs have a crucial role in the perception of these behaviorally relevant compounds as the genetic deletion of all or even individual olfactory TAARs can alter the behavioral response and reduce the sensitivity to amines. The small size of this receptor family combined with the ethological relevance of their ligands makes the TAARs an attractive model system for probing olfactory perception. This review will summarize the current knowledge on the olfactory TAARs and discuss whether they represent a unique subsystem within the main olfactory system.

Indexed as

AminesAnimalsOlfactory Receptor NeuronsAminesG protein-coupled receptor (GCPR)OlfactionOlfactory receptorPerceptionVolatile amines

Identifiers

PMID33237477
PMCPMC7878350
OpenAlexW3107123184

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.