SynthesisInternational urogynecology journal2021
Comparison of synthetic mesh erosion and chronic pain rates after surgery for pelvic organ prolapse and stress urinary incontinence: a systematic review.
Synthesis in International urogynecology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- A meta-analysis of the correlation between the duration of the second stage of labor and recent postpartum pelvic floor injury in primiparous.Frontiers in medicine · 2025Pooled it
- The impact of surgeon operative volume on risk of reoperation within 5 years of mid-urethral sling: a systematic review.International urogynecology journal · 2023Pooled it
- Pelvic pain and lower urinary tract symptoms; long-term comparison between women with and without mid-urethral sling insertion.Acta obstetricia et gynecologica Scandinavica · 2026Article
- A Retrospective Cohort Study Investigating the Clinical Care Pathway for Patients at a Pelvic Mesh Complications Clinic in a Western Australian Tertiary Hospital.The Australian & New Zealand journal of obstetrics & gynaecology · 2026Article
- Histological and transcriptomic analysis of paravaginal and central defects in anterior vaginal wall prolapse: Insights from DeLancey's pelvic floor theory.Histology and histopathology · 2025Article
- Developing items for inclusion in a new pain-specific patient-reported outcome measure for pelvic floor surgery: a mixed-methods study.Health and quality of life outcomes · 2025Article
- Toward Sex-Specific Biomaterials Innovation: A Perspective.ACS biomaterials science & engineering · 2025Review
- The management of vaginal prolapse and stress incontinence mesh complications in a quaternary mesh complications service in the United Kingdom (U.K): a 5-year observational study.BMC women's health · 2025Observational
- Changes in the Level of hs-CRP in the Blood and Morphometric Parameters of Tissues Following Implantation of Polypropylene.International journal of molecular sciences · 2025Article
- Treatment Strategies for Painful Pelvic Floor Conditions: A Focus on the Potential Benefits of Cannabidiol.Biomolecules · 2024Review
- Enhancing the autologous fascial sling procedure: A novel fixation method for treating stress urinary incontinence in female patients.Journal of the Chinese Medical Association : JCMA · 2024Article
- Analysis of British Columbia practice patterns in the management of female stress urinary incontinence with emphasis on mesh use.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2024Article
- Quality of life outcomes after transobturator tape full removal surgeries: A monocentric experience.BJUI compass · 2024Article
- Baseline measures for women with mesh complications accessing a pain service (as part of the London Complex Mesh Centre).British journal of pain · 2024Article
- Laparoscopic repair of an anterior perineal hernia: a video presentation.Facts, views & vision in ObGyn · 2023Article
- Total trans-obturator tape (TOT) removal; a case series including pain and urinary continence outcomes.International urogynecology journal · 2023Article
- Development and in vitro investigation of a biodegradable mesh for the treatment of stress urinary incontinence.International urogynecology journal · 2022Article
- Endometrial SUSD2Journal of personalized medicine · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
backgroundThe aim of this study is to systematically compare rates of erosion and chronic pain after mesh insertion for pelvic organ prolapse (POP) and stress urinary incontinence (SUI) surgery.
methodsA systematic electronic search was performed on studies that evaluated the incidence of erosion and chronic pain after mesh insertion for POP or SUI. The primary outcome measurement was to compare mesh erosion rates for POP and SUI surgery. Secondary outcome measurements were incidence of de novo pain and a comparison of patient demographics for both surgeries.
resultsTwenty-six studies on 292,606 patients (n = 9077 for POP surgery and n = 283,529 for SUI surgery) met the inclusion criteria. Median follow-up was 26.38 ± 22.17 months for POP surgery and 39.33 ± 27.68 months for SUI surgery. Overall, the POP group were older (p < 0.0001) and had a lower BMI (p < 0.0001). Mesh erosion rates were significantly greater in the POP group compared to the SUI group (4% versus 1.9%) (OR 2.13; 95% CI 1.91-2.37; p < 0.0001). The duration from surgery to onset of mesh erosion was 306.84 ± 183.98 days. There was no difference in erosion rates between abdominal and transvaginal mesh for POP. There was no difference in erosion rates between the transobturator and retropubic approach for SUI. The incidence of chronic pain was significantly greater in the POP group compared to the SUI group (6.7% versus 0.6%) (OR 11.02; 95% CI 8.15-14.9; p < 0.0001). The duration from surgery to onset of chronic pain was 325.88 ± 226.31 days.
conclusionsThe risk of mesh erosion and chronic pain is significantly higher after surgery for POP compared to SUI. These significant complications occur within the first year after surgery.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.