ArticleEinstein (Sao Paulo, Brazil)2020
Surgical antibiotic prophylaxis: is the clinical practice based on evidence?
Article in Einstein (Sao Paulo, Brazil), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 16 citations in OpenAlex.
- Patterns of Bacterial Infections Following Orthopedic Surgeries: A Retrospective Analysis.Cureus · 2026Article
- Application of PDCA cycle management in the rational use of perioperative antimicrobial prophylaxis in orthopedic clean surgery.European journal of medical research · 2025Article
- Current prescription trends in antibiotic prophylaxis: a multinational survey in esthetic plastic surgery.Annals of medicine and surgery (2012) · 2025Article
- Surgical Antibiotic Prophylaxis: A Proposal for a Global Evidence-Based Bundle.Antibiotics (Basel, Switzerland) · 2024Review
- [Modern management of chronic wounds].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2021Article
- Prolonged antibiotic prophylaxis use in elective orthopaedic surgery - a cross-sectional analysis.BMC musculoskeletal disorders · 2021Article
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess the surgical antibiotic prophylaxis.
methodsThis was a descriptive study performed at a public tertiary care university hospital gathering prescription, sociodemographic and hospitalization data of inpatients admitted in 2014 who used antimicrobial drugs. This data were obtained from the hospital electronic database. The antimicrobial data were classified according to the anatomical, therapeutic chemical/defined daily dose per 1,000 inpatients. An exploratory analysis was performed using principal component analysis.
resultsA total of 5,182 inpatients were prescribed surgical antibiotic prophylaxis. Of the total antimicrobial use, 11.7% were for surgical antibiotic prophylaxis. The orthopedic, thoracic and cardiovascular postoperative units, and postoperative intensive care unit comprised more than half of the total surgical antibiotic prophylaxis use (56.3%). The duration of antimicrobial use of these units were 2.2, 2.0, and 1.4 days, respectively. Third-generation cephalosporins and fluoroquinolones had the longest use among antimicrobial classes.
conclusionSurgical antibiotic prophylaxis was inadequate in the orthopedic, postoperative intensive care, thoracic and cardiovascular postoperative, gynecology and obstetrics, and otolaryngology units. Therefore, the development and implementation of additional strategies to promote surgical antibiotic stewardship at hospitals are essential.
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