Evidence map›Paper›PMID 33236841›Full record

ArticleInternational wound journal2021

Negative pressure wound therapy in spinal fusion patients.

Asad S Akhter, Benjamin G McGahan, Liesl Close, David Dornbos, Nathaniel Toop, Nicholas R Thomas, Elizabeth Christ, Nader S Dahdaleh, Andrew J Grossbach

Open access · hybridAbstract read
In one paragraph

Article in International wound journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Can prophylactic negative pressure wound therapy improve clinical outcomes in spinal fusion surgery? A meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2022
    Pooled it
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  12. Negative Pressure Wound Therapy in Spinal Surgery.Bioengineering (Basel, Switzerland) · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Asad S AkhterDepartment of Neurosurgery, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Benjamin G McGahanDepartment of Neurosurgery, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Liesl CloseDepartment of Neurosurgery, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA.
David DornbosDepartment of Neurosurgery, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Nathaniel ToopDepartment of Neurosurgery, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Nicholas R ThomasSchool of Medicine, Northeast Ohio Medical University, Rootstown, Ohio, USA.
Elizabeth ChristDepartment of Neurosurgery, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Nader S DahdalehDepartment of Neurosurgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Andrew J GrossbachDepartment of Neurosurgery, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
The Ohio State University Wexner Medical Center · USNortheast Ohio Medical University · USNorthwestern University · USUniversity of Iowa · US

Funding

Acelity KCI
6 · The paper itself

Abstract

Post-operative wound complications are some of the most common acute complications following spine surgery. These surgical site infections (SSI) contribute to increased healthcare related costs. Negative pressure wound therapy (NPWT) has long been used for treatment of soft tissue injury or defects. NPWT may reduce the incident of SSI following spinal fusion procedures; however, its potential applications need further clarification. Thus, we conducted a retrospective analysis of two cohorts to compare NPWT to traditional sterile dressings following spinal fusions in regards to post-operative outcomes. Following institutional review board approval, 42 patients who had a NPWT were matched by type of surgery to 42 patients who had traditional dressings. A retrospective chart-review was completed. Outcome measures, particularly SSI and need for reoperation, were analyzed using one-way ANOVA for both univariate and multivariate analysis. When controlled for sex and body-mass index, the use of a NPWT was independently correlated with decreased SSI (P = .035). Superficial dehiscence, seroma, need for additional outpatient care, and need for operative revision were all found to occur at higher rates in the traditional dressing cohort. Closed incisional negative pressure wound therapy provides a cost-effective method of decreasing surgical site infection for posterior elective spine surgeries.

Indexed as

Negative-Pressure Wound TherapySpinal FusionAgedBandagesFemaleHumansMaleMiddle AgedRetrospective StudiesSeromaSurgical Wound DehiscenceSurgical Wound Infectionfusionnegative pressure wound therapyoutcomesspinesurgical site infection

Identifiers

PMID33236841
PMCPMC8243993
OpenAlexW3107283955

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.