Evidence map›Paper›PMID 33236827›Full record

ArticleJournal of applied clinical medical physics2020

Methodological approach to create an atlas using a commercial auto-contouring software.

Marta Casati, Stefano Piffer, Silvia Calusi, Livia Marrazzo, Gabriele Simontacchi, Vanessa Di Cataldo, Daniela Greto, Isacco Desideri, Marco Vernaleone, Giulio Francolini and 2 more

Abstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Marta CasatiDepartment of Medical Physics, Careggi University Hospital, Florence, Italy.ORCID https://orcid.org/0000-0003-1863-6755
Stefano PifferDepartment of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy.
Silvia CalusiDepartment of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy.
Livia MarrazzoDepartment of Medical Physics, Careggi University Hospital, Florence, Italy.
Gabriele SimontacchiDepartment of Radiation Oncology, Careggi University Hospital, Florence, Italy.
Vanessa Di CataldoFlorentine Institute of Care and Assistance (IFCA), Florence, Italy.
Daniela GretoDepartment of Radiation Oncology, Careggi University Hospital, Florence, Italy.
Isacco DesideriDepartment of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy.
Marco VernaleoneDepartment of Radiation Oncology, Careggi University Hospital, Florence, Italy.
Giulio FrancoliniDepartment of Radiation Oncology, Careggi University Hospital, Florence, Italy.
Lorenzo LiviDepartment of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy.
Stefania PallottaDepartment of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy.ORCID https://orcid.org/0000-0003-4123-7971

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this work was to establish a methodological approach for creation and optimization of an atlas for auto-contouring, using the commercial software MIM MAESTRO (MIM Software Inc. Cleveland OH).

methodsA computed tomography (CT) male pelvis atlas was created and optimized to evaluate how different tools and options impact on the accuracy of automatic segmentation. Pelvic lymph nodes (PLN), rectum, bladder, and femurs of 55 subjects were reviewed for consistency by a senior consultant radiation oncologist with 15 yr of experience. Several atlas and workflow options were tuned to optimize the accuracy of auto-contours. The deformable image registration (DIR), the finalization method, the k number of atlas best matching subjects, and several post-processing options were studied. To test our atlas performances, automatic and reference manual contours of 20 test subjects were statistically compared based on dice similarity coefficient (DSC) and mean distance to agreement (MDA) indices. The effect of field of view (FOV) reduction on auto-contouring time was also investigated.

resultsWith the optimized atlas and workflow, DSC and MDA median values of bladder, rectum, PLN, and femurs were 0.91 and 1.6 mm, 0.85 and 1.6 mm, 0.85 and 1.8 mm, and 0.96 and 0.5 mm, respectively. Auto-contouring time was more than halved by strictly cropping the FOV of the subject to be contoured to the pelvic region.

conclusionA statistically significant improvement of auto-contours accuracy was obtained using our atlas and optimized workflow instead of the MIM Software pelvic atlas.

Indexed as

Radiotherapy Planning, Computer-AssistedTomography, X-Ray ComputedHumansMalePelvisRectumSoftwareatlasautomatic contouringCTmethodological approachpelvisradiotherapysegmentation

Identifiers

PMID33236827
PMCPMC7769405

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.