Evidence map›Paper›PMID 33236539›Full record

ArticleKorean journal of radiology2021

Clinically Available Software for Automatic Brain Volumetry: Comparisons of Volume Measurements and Validation of Intermethod Reliability.

Ji Young Lee, Se Won Oh, Mi Sun Chung, Ji Eun Park, Yeonsil Moon, Hong Jun Jeon, Won Jin Moon

Abstract read
In one paragraph

Article in Korean journal of radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ji Young LeeDepartment of Radiology, Hanyang University Medical Center, Seoul, Korea.ORCID 0000-0003-1181-8070
Se Won OhDepartment of Radiology, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID 0000-0003-1336-4498
Mi Sun ChungDepartment of Radiology, Chung-Ang University Hospital, Seoul, Korea.ORCID 0000-0003-1141-9555
Ji Eun ParkDepartment of Radiology, Asan Medical Center, Seoul, Korea.ORCID 0000-0002-4419-4682
Yeonsil MoonDepartment of Neurology, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea.ORCID 0000-0001-7770-4127
Hong Jun JeonDepartment of Psychiatry, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea.ORCID 0000-0002-0260-0494
Won Jin MoonDepartment of Radiology, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea. mdmoonwj@kuh.ac.kr.ORCID 0000-0002-8925-7376

Funding

Konkuk University Medical Center
6 · The paper itself

Abstract

objectiveTo compare two clinically available MR volumetry software, NeuroQuant® (NQ) and Inbrain® (IB), and examine the inter-method reliabilities and differences between them. MATERIALS AND

methodsThis study included 172 subjects (age range, 55-88 years; mean age, 71.2 years), comprising 45 normal healthy subjects, 85 patients with mild cognitive impairment, and 42 patients with Alzheimer's disease. Magnetic resonance imaging scans were analyzed with IB and NQ. Mean differences were compared with the paired t test. Inter-method reliability was evaluated with Pearson's correlation coefficients and intraclass correlation coefficients (ICCs). Effect sizes were also obtained to document the standardized mean differences.

resultsThe paired t test showed significant volume differences in most regions except for the amygdala between the two methods. Nevertheless, inter-method measurements between IB and NQ showed good to excellent reliability (0.72 <

conclusionComparisons between IB and NQ showed significantly different volume measurements with large effect sizes. However, they showed good to excellent inter-method reliability in volumetric measurements for all brain regions, with the exception of the pallidum. Clinicians using these commercial software should take into consideration that different volume measurements could be obtained depending on the software used.

Indexed as

SoftwareAgedAged, 80 and overAlzheimer DiseaseBrainCase-Control StudiesCognitive DysfunctionFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedReproducibility of ResultsAlzheimer's diseaseBrain volumetryMRINeuroQuant®ReliabilitySoftwares

Identifiers

PMID33236539
PMCPMC7909859

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.