ArticleEnvironmental science and pollution research international2021
Melatonin alleviates cadmium toxicity by reducing nitric oxide accumulation and IRT1 expression in Chinese cabbage seedlings.
Article in Environmental science and pollution research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 66 citations in OpenAlex.
- Melatonin pre-treatment mitigates cadmium toxicity in maize seedlings by regulating hydrological status, physio-biochemical, and hormonal responses.BMC plant biology · 2026Article
- Plant melatonin: roles and regulatory mechanisms in plant growth, development, and responses to biotic and abiotic stresses.Plant signaling & behavior · 2025Review
- Synergistic role of gamma-aminobutyric acid and melatonin in mitigating lead stress in rice.BMC plant biology · 2025Article
- Nano-silica improves the emergence of pepper seeds and the growth of seedlings under waterlogging stress by reducing oxidative damage.BMC plant biology · 2025Article
- Exogenous Nitric Oxide Promotes the Growth and Cadmium Accumulation of Alfalfa (Plants (Basel, Switzerland) · 2025Article
- Review
- Exogenous Application of Amino Acids Alleviates Toxicity in Two Chinese Cabbage Cultivars by Modulating Cadmium Distribution and Reducing Its Translocation.International journal of molecular sciences · 2024Article
- Physiological and Transcriptomic Analysis Reveals That Melatonin Alleviates Aluminum Toxicity in Alfalfa (International journal of molecular sciences · 2023Article
- Curative Potential of Substances with Bioactive Properties to Alleviate Cd Toxicity: A Review.International journal of environmental research and public health · 2022Review
- Interaction between Melatonin and NO: Action Mechanisms, Main Targets, and Putative Roles of the Emerging Molecule NOmela.International journal of molecular sciences · 2022Review
- Crosstalk between Melatonin and Reactive Oxygen Species in Plant Abiotic Stress Responses: An Update.International journal of molecular sciences · 2022Review
- Differential Impact of Nitric Oxide and Abscisic Acid on the Cellular and Physiological Functioning ofPlants (Basel, Switzerland) · 2022Article
- Physiological Mechanism of Exogenous 5-Aminolevulinic Acid Improved the Tolerance of Chinese Cabbage (Frontiers in plant science · 2022Article
- Salicylic Acid Regulates Indole-3-Carbinol Biosynthesis Under Blue Light in Broccoli Sprouts (Frontiers in plant science · 2022Article
- Melatonin Confers Plant Cadmium Tolerance: An Update.International journal of molecular sciences · 2021Review
- ROS and NO Phytomelatonin-Induced Signaling Mechanisms under Metal Toxicity in Plants: A Review.Antioxidants (Basel, Switzerland) · 2021Review
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Melatonin (MT) is reported as a kind of phytohormone, exerts various biological activities, mediating plant growth and development and responding to abiotic stresses. In the present research, we examined the possibility that MT could involve in the alleviation of cadmium (Cd) toxicity by reducing the accumulation of nitric oxide (NO). The research indicated that the addition of MT significantly increased the biomass and photosynthetic parameters of plants compared with the control treated under Cd stress. Besides, we found that compared with the control treatment, MT also reduced the level of Cd-induced nitric oxide, and at the same time, the enzyme activity related to NO synthesis and the expression of related genes were decreased. In addition, MT treatment significantly reduced the Cd content in Chinese cabbage seedlings compared with the control, which was partially reversed by the addition of SNP (NO donor). PTIO (NO scavenger) addition could reduce the Cd content when seedlings were exposed to Cd stress. At the same time, compared with the Cd stress, the concentration of Cd in MT-treated plants decreased significantly, and the expression levels of related transport genes IRT1 also decreased significantly. Taken together, these results further support the idea that under the stress of Cd, NO increases the expression of IRT1, thus further increasing the absorption of Cd and aggravating the stress of Cd in plants, while exogenously added MT can inhibit the synthesis of NO, reduce the content of Cd, and alleviate the stress caused by Cd.
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