Evidence map›Paper›PMID 33236109›Full record

SynthesisJournal of the American Medical Informatics Association : JAMIA2021

Effects of technology-supported exercise programs on the knee pain, physical function, and quality of life of individuals with knee osteoarthritis and/or chronic knee pain: A systematic review and meta-analysis of randomized controlled trials.

Tianrong Chen, Calvin Kalun Or, Jiayin Chen

Registry-linked trialOpen access · greenAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of the American Medical Informatics Association : JAMIA, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05173064 (Development and Randomized Controlled Trial of an AI-powered Technological Surrogate Physiotherapist), which is not on this map. Cited by 44 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 14 pooled it
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05173064 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Development and Randomized Controlled Trial of an AI-powered Technological Surrogate Physiotherapist (TSP) Dedicated to Quality Enhancement and Cost Reduction in Knee Osteoarthritis Exercise Rehabilitation

TypeinterventionalSponsorThe University of Hong KongRan2026 to 2027Enrolled176ConditionsPain, Knee OsteoarthritisArmsThe AI-powered Technological Surrogate Physiotherapist, Face-to-face physiotherapist-supervised exercise program
3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 14 syntheses or guidelines pooled it, 93 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Tianrong ChenDepartment of Industrial and Manufacturing Systems Engineering, The University of Hong Kong, Hong Kong, China.
Calvin Kalun OrDepartment of Industrial and Manufacturing Systems Engineering, The University of Hong Kong, Hong Kong, China.
Jiayin ChenDepartment of Industrial and Manufacturing Systems Engineering, The University of Hong Kong, Hong Kong, China.
University of Hong Kong · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe study sought to examine the effects of technology-supported exercise programs on the knee pain, physical function, and quality of life of individuals with knee osteoarthritis and/or chronic knee pain by a systematic review and meta-analysis of randomized controlled trials. MATERIALS AND

methodsWe searched MEDLINE, EMBASE, CINAHL Plus, and the Cochrane Library from database inception to August 2020. A meta-analysis and subgroup analyses, stratified by technology type and program feature, were conducted.

resultsTwelve randomized controlled trials were reviewed, all of which implemented the programs for 4 weeks to 6 months. Telephone, Web, mobile app, computer, and virtual reality were used to deliver the programs. The meta-analysis showed that these programs were associated with significant improvements in knee pain (standardized mean difference [SMD] = -0.29; 95% confidence interval [CI], -0.48 to -0.10; P = .003) and quality of life (SMD = 0.25; 95% CI, 0.04 to 0.46; P = .02) but not with significant improvement in physical function (SMD = 0.22; 95% CI, 0 to 0.43; P = .053). Subgroup analyses showed that some technology types and program features were suggestive of potential benefits.

conclusionsUsing technology to deliver the exercise programs appears to offer benefits. The technology types and program features that were associated with health values have been identified, based on which suggestions are discussed for the further research and development of such programs.

Indexed as

Quality of LifeTelerehabilitationArthralgiaChronic PainComputersExercise TherapyHumansKnee JointMobile ApplicationsOsteoarthritis, KneeRandomized Controlled Trials as TopicTelephoneVirtual Realityexercise therapyknee osteoarthritisknee painmeta-analysissystematic review

Identifiers

PMID33236109
PMCPMC7883981
OpenAlexW3106603484

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.