Evidence map›Paper›PMID 33235912›Full record

ArticleMolecular & cellular oncology2020

Extracellular vesicles as potential tools for regenerative therapy.

Jose Antonio Rodriguez-Navarro, Jorge Pascual-Guerra, Silvia Sacristan, Maria Del Carmen Nogales, Juan Antonio Fafián-Labora, Ana O'Loghlen

Abstract read
In one paragraph

Article in Molecular & cellular oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jose Antonio Rodriguez-NavarroInstituto Ramón y Cajal de Investigaciones Sanitarias, IRYCIS Neurobiología-Investigación, Madrid, Spain.
Jorge Pascual-GuerraInstituto Ramón y Cajal de Investigaciones Sanitarias, IRYCIS Neurobiología-Investigación, Madrid, Spain.ORCID https://orcid.org/0000-0001-6667-3310
Silvia SacristanInstituto Ramón y Cajal de Investigaciones Sanitarias, IRYCIS Neurobiología-Investigación, Madrid, Spain.ORCID https://orcid.org/0000-0001-5294-7608
Maria Del Carmen NogalesInstituto Ramón y Cajal de Investigaciones Sanitarias, IRYCIS Neurobiología-Investigación, Madrid, Spain.
Juan Antonio Fafián-LaboraEpigenetics & Cellular Senescence Group, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Ana O'LoghlenEpigenetics & Cellular Senescence Group, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.ORCID https://orcid.org/0000-0002-8141-1965

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Small extracellular vesicles released by fibroblasts from young human donors diminish lipid peroxidation in senescent cells and in different old mice organs due to their enrichment in Glutathione-S-transferase Mu lipid antioxidant activity.

Indexed as

agingglutathione-S-transferase Mlipid peroxidationsenescenceSmall extracellular vesicles

Identifiers

PMID33235912
PMCPMC7671023

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.