Evidence map›Paper›PMID 33235899›Full record

ArticleInternational journal of cardiology. Heart & vasculature2020

Association between frailty and self-reported health following heart valve surgery.

Britt Borregaard, Jordi S Dahl, Sandra B Lauck, Jesper Ryg, Selina K Berg, Ola Ekholm, Jeroen M Hendriks, Lars P S Riber, Tone M Norekvål, Jacob E Møller

Open access · goldAbstract read
In one paragraph

Article in International journal of cardiology. Heart & vasculature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Frailty and Cardiovascular Risk.European cardiology · 2026
    Review
  2. Article
  3. Frailty Indices and Their Importance in Elderly Patients: A Perspective Review.Journal of community hospital internal medicine perspectives · 2024
    Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 5 countries.

Britt BorregaardDepartment of Cardiology, Odense University Hospital, Denmark.
Jordi S DahlDepartment of Cardiology, Odense University Hospital, Denmark.
Sandra B LauckCentre for Heart Valve Innovation, St. Paul's Hospital, Canada.
Jesper RygUniversity of Southern Denmark, Denmark.
Selina K BergDepartment of Clinical Medicine, University of Copenhagen, Denmark.
Ola EkholmUniversity of Southern Denmark, Denmark.
Jeroen M HendriksCentre for Heart Rhythm Disorders, South Australian Health and Medical Research Institute, Royal Adelaide Hospital, Australia.
Lars P S RiberDepartment of Cardiothoracic and Vascular Surgery, Odense University Hospital, Denmark.
Tone M NorekvålDepartment of Heart Disease, Haukeland University Hospital, Norway.
Jacob E MøllerDepartment of Cardiology, Odense University Hospital, Denmark.
University of Southern Denmark · DKLinköping University · SEUniversity of British Columbia · CAUniversity of Copenhagen · DKWestern Norway University of Applied Sciences · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundKnowledge about the association between frailty and self-reported health among patients undergoing heart valve surgery remains sparse. Thus, the objectives were to I) describe changes in self-reported health at different time points according to frailty status, and to II) investigate the association between frailty status at discharge and poor self-reported health four weeks after discharge among patients undergoing heart valve surgery.

methodsIn a prospective cohort study, consecutive patients undergoing heart valve surgery, including transapical/transaortic valve procedures were included. Frailty was measured using the Fried score, and self-reported health using the Kansas City Cardiomyopathy Questionnaire (KCCQ) and the EuroQoL-5 Dimensions 5-Levels Health Status Questionnaire (EQ-5D-5L).To investigate the association between frailty and self-reported health, multivariable logistic regression models were used. Analyses were adjusted for sex, age, surgical risk evaluation (EuroScore) and procedure and presented as odds ratios (OR) with 95% confidence intervals (CI).

resultsFrailty was assessed at discharge in 288 patients (median age 71, 69% men); 51 patients (18%) were frail. In the multivariable analyses, frailty at discharge remained significantly associated with poor self-reported health at four weeks, OR (95% CI): EQ-5D-5L Index 3.38 (1.51-7.52), VAS 2.41 (1.13-5.14), and KCCQ 2.84 (1.35-5.97).

conclusionFrailty is present at discharge in 18% of patients undergoing heart valve surgery, and being frail is associated with poor self-reported health at four weeks of follow-up. This supports a clinical need to address the unique risk of frail patients among heart valve teams broadly, and not only to measure frailty as a marker of operative risk.

Indexed as

Cardiac surgeryFrailtyHealth-related quality of lifeHeart valves

Identifiers

PMID33235899
PMCPMC7670239
OpenAlexW3103617230

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.