Evidence map›Paper›PMID 33235731›Full record

ArticleMolecular and clinical oncology2021

Impact of postoperative reduced skeletal muscle on prognosis after recurrence in gastric cancer.

Keita Kouzu, Hironori Tsujimoto, Hidekazu Sugasawa, Yusuke Ishibashi, Yujiro Itazaki, Satoshi Tsuchiya, Yoji Kishi, Hideki Ueno

Open access · diamondAbstract read
In one paragraph

Article in Molecular and clinical oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Gastric Cancer with Sarcopenia: an Area Worth Focusing On.Current treatment options in oncology · 2023
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Keita KouzuDepartment of Surgery, National Defense Medical College, Tokorozawa, Saitama 359-0042, Japan.
Hironori TsujimotoDepartment of Surgery, National Defense Medical College, Tokorozawa, Saitama 359-0042, Japan.
Hidekazu SugasawaDepartment of Surgery, National Defense Medical College, Tokorozawa, Saitama 359-0042, Japan.
Yusuke IshibashiDepartment of Surgery, National Defense Medical College, Tokorozawa, Saitama 359-0042, Japan.
Yujiro ItazakiDepartment of Surgery, National Defense Medical College, Tokorozawa, Saitama 359-0042, Japan.
Satoshi TsuchiyaDepartment of Surgery, National Defense Medical College, Tokorozawa, Saitama 359-0042, Japan.
Yoji KishiDepartment of Surgery, National Defense Medical College, Tokorozawa, Saitama 359-0042, Japan.
Hideki UenoDepartment of Surgery, National Defense Medical College, Tokorozawa, Saitama 359-0042, Japan.
National Defense Medical College · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Little is known about the association between sarcopenia development after gastrectomy and gastric cancer prognosis after recurrence. The present study retrospectively examined the effects of decreased psoas muscle index (PMI) on post-recurrence prognosis after gastrectomy. A total of 67 patients with gastric cancer recurrence were included in the present study. PMI at pre-operation and recurrence were calculated, and 25 patients whose PMI reduction rate value was lower than the cutoff values (male=0.766 and female=0.704) were classified into the sarcopenia group and 42 patients into the non-sarcopenia group. There were no significant differences between the groups regarding age, sex, pathological stage, and nutrition and inflammation indices at the time of recurrence. Post-recurrence overall survival (OS) was significantly shorter in the sarcopenia group compared with the non-sarcopenia group (P<0.001). The post-recurrence survival rate was significantly worse in the sarcopenia group compared with the non-sarcopenia group (P<0.001). In multivariate analysis, sarcopenia (HR=5.04) and the total courses of chemotherapy after recurrence (HR=3.88) were independent unfavorable prognostic factors. In conclusion, sarcopenia and fewer total courses of post-recurrence chemotherapy were poor prognostic factors after gastric cancer recurrence. To improve prognosis, preventing sarcopenia development after gastrectomy is required.

Indexed as

chemotherapygastric cancerprognosissarcopenia

Identifiers

PMID33235731
PMCPMC7678615
OpenAlexW3096318488

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.