ArticlePakistan journal of medical sciences
Comparison of the clinical application values of PCT, hs-CRP and SAA detection in the early diagnosis of sepsis.
Article in Pakistan journal of medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 18 citations in OpenAlex.
- Impact of thoracoscopic segmental lung resection versus wedge on early post-operative recovery and short-term prognosis in elderly patients with early non-small cell lung cancer: A retrospective non-randomised controlled cohort study.Journal of minimal access surgery · 2026Article
- The Diagnostic and Prognostic Value of Procalcitonin and High-Sensitivity C-Reactive Protein in Early-Stage Burn Sepsis: A Retrospective Cohort Study.Journal of inflammation research · 2026Article
- C-reactive protein in adult sepsis: systematic review and meta-analysis.Clinics (Sao Paulo, Brazil) · 2025Review
- Efficacy of Zhibitai combined with Atorvastatin on blood lipid and inflammation in patients with coronary heart disease.Pakistan journal of medical sciences · 2025Article
- Construction and verification of a nomogram model for the risk of death in sepsis patients.Scientific reports · 2025Article
- Single-Cell RNA-Seq Uncovers Cellular Heterogeneity from Deep Fascia in Necrotizing Fasciitis Patients.Journal of inflammation research · 2025Article
- Comparative analysis of inflammatory biomarkers for the diagnosis of neonatal sepsis: IL-6, IL-8, SAA, CRP, and PCT.Open life sciences · 2025Article
- [Diagnostic Value of Interleukin 6, Interleukin 12P70, Serum Amyloid A, and Procalcitonin for Rheumatoid Arthritis and Their Relationship With the Disease Activity].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024Article
- Long non‑coding RNAs MALAT1, NEAT1 and DSCR4 can be serum biomarkers in predicting urosepsis occurrence and reflect disease severity.Experimental and therapeutic medicine · 2024Article
- PCT, IL-6, and IL-10 facilitate early diagnosis and pathogen classifications in bloodstream infection.Annals of clinical microbiology and antimicrobials · 2023Article
- Clinical diagnostic value of IL-14, 1L-16 and SAA in periodontitis.Clinical oral investigations · 2023Article
- Kaempferol improves acute kidney injury via inhibition of macrophage infiltration in septic mice.Bioscience reports · 2023Article
- Multi-marker approach using C-reactive protein, procalcitonin, neutrophil CD64 index for the prognosis of sepsis in intensive care unit: a retrospective cohort study.BMC infectious diseases · 2022Article
- Biomarkers for sepsis: more than just fever and leukocytosis-a narrative review.Critical care (London, England) · 2022Review
- Value of CRP, PCT, and NLR in Prediction of Severity and Prognosis of Patients With Bloodstream Infections and Sepsis.Frontiers in surgery · 2022Article
- Correlation analysis of systemic immune inflammatory index, Serum IL-35 and HMGB-1 with the severity and prognosis of sepsis.Pakistan journal of medical sciencesArticle
- Study on the correlation and clinical significance of T-lymphocyte Subsets, IL-6 and PCT in the severity of patients with sepsis.Pakistan journal of medical sciencesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo investigate the clinical application values of procalcitonin (PCT), high-sensitivity C-reactive protein (hs-CRP) and serum amyloid A (SAA) in the early diagnosis of sepsis.
methodsIn this retrospective analysis, 36 patients admitted to Liaocheng People's Hospital were selected from May 2018 to July 2019. According to infectious disease diagnostic criteria, 17 patients were confirmed to have sepsis (observation group), and 19 patients were determined to be nonseptic (control group). The levels of PCT, CRP and SAA of patients were detected on admission, and the clinical application values of PCT, CRP and SAA for sepsis were compared.
resultsSeventeen patients were included in the observation group, including 9 males and 8 females, with an average age of 52.18 ± 9.49 years; 19 patients were included in the control group, including 12 males and 7 females, with an average age of 51.53 ± 8.50 years. On admission, there were significant differences in white blood cell (WBC) count (
conclusionCompared with hs-CRP and SAA, PCT had a higher clinical application value for sepsis, and PCT could be used as a reliable index for the early diagnosis of sepsis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.