ArticleChemical engineering journal (Lausanne, Switzerland : 1996)2021
Plasma-activated water: An alternative disinfectant for S protein inactivation to prevent SARS-CoV-2 infection.
Article in Chemical engineering journal (Lausanne, Switzerland : 1996), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
49 citing papers in PubMed, 175 citations in OpenAlex.
- Nebulized inhalation of plasma-activated water in the treatment of progressive moderate COVID-19 patients with antiviral treatment failure: a randomized controlled pilot trial.BMC infectious diseases · 2024Trial
- Optimized methods for adsorbable organic halides (AOX) and halogen‑specific speciation for tracking disinfection by-products from source to tap.Analytical and bioanalytical chemistry · 2026Article
- Removal of nitrogen and emerging pollutants from anaerobically treated effluents from domestic wastewater, using nitritation/anammox: a state of art review.Biodegradation · 2026Review
- Removal of nitrogen and emerging pollutants from anaerobically treated effluents from domestic wastewater, using nitritation/anammox: a state of art review.Biodegradation · 2026Review
- Air-fed cold atmospheric plasma device as a safe and effective anti-SARS-CoV-2 air filter.Scientific reports · 2026Article
- Article
- A portable electrochemical device with UiO-66@polydopamine modified screen-printed electrodes for rapid detection of manganese ions.Mikrochimica acta · 2025Article
- Inactivation of Pseudovirus Expressing the D614G Spike Protein Mutation using Nitric Oxide-Plasma Activated Water.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Article
- Plasma-activated water: Candidate hand disinfectant for SARS-CoV-2 transmission disruption.Heliyon · 2024Article
- Atmospheric non-thermal plasma inactivation of Ascosphaera apis, the causative agent of chalkbrood disease in honeybee.Scientific reports · 2024Article
- Persistence of Coronavirus on Surface Materials and Its Control Measures Using Nonthermal Plasma and Other Agents.International journal of molecular sciences · 2023Review
- Effects of Nitro-Oxidative Stress on Biomolecules: Part 1-Non-Reactive Molecular Dynamics Simulations.Biomolecules · 2023Review
- Hydroxyapatite coatings on cement paste as barriers against radiological contamination.Scientific reports · 2023Article
- Inhibition of Fungal Growth and Aflatoxin BFoods (Basel, Switzerland) · 2023Article
- Plasma-Activated Hydrogels for Microbial Disinfection.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Solar desalination/purification (solar stills, humidification-dehumidification, solar disinfection) in high altitude during COVID19: Insights of gastrointestinal manifestations and systems' mechanism.Journal of hazardous materials advances · 2023Article
- Physicochemical Properties of Plasma-Activated Water and Its Control Effects on the Quality of Strawberries.Molecules (Basel, Switzerland) · 2023Article
- Efficient inactivation of the contamination with pathogenic microorganisms by a combination of water spray and plasma-activated air.Journal of hazardous materials · 2023Article
- DNA Strand Breaks and Denaturation as Probes of Chemical Reactivity versus Thermal Effects of Atmospheric Pressure Plasma Jets.ACS omega · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
SARS-CoV-2 is a highly contagious virus and is causing a global pandemic. SARS-CoV-2 infection depends on the recognition of and binding to the cellular receptor human angiotensin-converting enzyme 2 (hACE2) through the receptor-binding domain (RBD) of the spike protein, and disruption of this process can effectively inhibit SARS-CoV-2 invasion. Plasma-activated water efficiently inactivates bacteria and bacteriophages by causing damage to biological macromolecules, but its effect on coronavirus has not been reported. In this study, pseudoviruses with the SARS-CoV-2 S protein were used as a model, and plasma-activated water (PAW) effectively inhibited pseudovirus infection through S protein inactivation. The RBD was used to study the molecular details, and the RBD binding activity was inactivated by plasma-activated water through the RBD modification. The short-lived reactive species in the PAW, such as ONOO
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.