ArticlePsychology research and behavior management2020
Epigenetic Alterations of the Promoter Region of the
Article in Psychology research and behavior management, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT05765864 (Influences on and Prevention of Self-harm Behaviour Among the Most At-risk Adolescents), which is not on this map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Influences on and Prevention of Self-harm Behaviour Among the Most At-risk Adolescents
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- Genetics and epigenetics of self-injurious thoughts and behaviors: Systematic review of the suicide literature and methodological considerations.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2022Pooled it
- Pooled it
- [Research progress on influencing factors and biological mechanisms of non-suicidal self-injury in children and adolescents].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2026Review
- Beyond satiety: unraveling the complex roles of POMC neurons in behavior and metabolism.Reviews in endocrine & metabolic disorders · 2026Review
- Whole Blood Transcriptome Analysis in Female Adolescents With Depression Accompanied by Nonsuicidal Self-Injury and Suicide Attempt.Depression and anxiety · 2026Observational
- Overweight and POMC methylation: epigenetic associations with adolescent depression.BMC psychiatry · 2025Article
- Evaluation of Proopiomelanocortin (POMC) and neuropeptide Y (NPY) levels in bipolar and unipolar patients.BMC psychiatry · 2025Article
- Mediation of DNA methylation (cg04622888 and cg05037505) in the association between childhood maltreatment and non-suicidal self-injury in early adolescents.European child & adolescent psychiatry · 2025Article
- Epigenetics and suicidal behavior in adolescents: a critical review.Epigenomics · 2025Review
- Distinct correlation network of clinical characteristics in suicide attempters having adolescent major depressive disorder with non-suicidal self-injury.Translational psychiatry · 2024Article
- Progesterone receptor distribution in the human hypothalamus and its association with suicide.Acta neuropathologica communications · 2024Article
- Risk factors, theoretical models, and biological mechanisms of nonsuicidal self-injury: a brief review.Interdisciplinary nursing research · 2023Review
- DNA Methylation of POMC and NR3C1-1F and Its Implication in Major Depressive Disorder and Electroconvulsive Therapy.Pharmacopsychiatry · 2023Article
- Potential mechanisms of non-suicidal self-injury (NSSI) in major depressive disorder: a systematic review.General psychiatry · 2023Article
- DNA Methylation in Depression and Depressive-Like Phenotype: Biomarker or Target of Pharmacological Intervention?Current neuropharmacology · 2022Review
- Metabolomic biomarkers related to non-suicidal self-injury in patients with bipolar disorder.BMC psychiatry · 2022Article
Corrections and comments
- Erratum issued
Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe incidence of nonsuicidal self-injury (NSSI) behavior among adolescents increases year by year. Patients with a history of both depression and NSSI behaviors tend to have greater risk of suicide. At present, the mechanism of adolescent depressive disorder patients with NSSI behaviors is not clear, epigenetic mechanism may be involved. Proopiomelanocortin (
methodsBisulfite Sequencing PCR (BSP) was used to test the methylation level of
resultsBSP analysis found that the
conclusionThere was abnormal methylation in the
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.