Evidence map›Paper›PMID 33235441›Full record

ArticleDrug design, development and therapy2020

Efficacy and Safety of Supplemental Transarterial Chemoembolization Through Extrahepatic Collateral Arteries with Drug-eluting Beads: Treatment for Unresectable Hepatocellular Carcinoma.

Sung-Hua Chiu, Ping-Ying Chang, Yu-Lueng Shih, Wen-Yen Huang, Kai-Hsiung Ko, Wei-Chou Chang, Guo-Shu Huang

Open access · goldAbstract read
In one paragraph

Article in Drug design, development and therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Sung-Hua ChiuDepartment of Radiology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Ping-Ying ChangDivision of Hematology/Oncology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Yu-Lueng ShihDivision of Gastroenterology, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Wen-Yen HuangDepartment of Radiotherapy, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Kai-Hsiung KoDepartment of Radiology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Wei-Chou ChangDepartment of Radiology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Guo-Shu HuangDepartment of Radiology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Tri-Service General Hospital · TWNational Defense Medical Center · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the therapeutic efficacy and safety of supplement transarterial chemoembolization (TACE) with drug-eluting beads TACE (DEB-TACE) through extrahepatic collateral (EHC) arteries for the treatment of hepatocellular carcinoma (HCC). PATIENTS AND

methodsIn this retrospective study, 61 unresectable HCC patients with treatment-naïve EHC blood supplies who received TACE from January 2016 to March 2019 were enrolled; of these patients, 42 (68.9%) received DEB-TACE, and 19 (31.1%) received cTACE. The hepatic tumor feeding arteries were treated in the same TACE session if it presented. The tumor response, time-to-progression (TTP), and overall survival (OS) were analyzed. Safety was assessed based on the occurrence of liver function deterioration and major complications within three months after TACE.

resultsDEB-TACE showed better efficacy than cTACE in the disease control rate (

conclusionDEB-TACE through EHC arteries has a potential therapeutic effect in the treatment of unresectable HCC, with comparable safety compared with cTACE.

Indexed as

Chemoembolization, TherapeuticAdultAgedAged, 80 and overAntineoplastic AgentsArteriesCarcinoma, HepatocellularCollateral CirculationFemaleHumansLiver NeoplasmsMaleMiddle AgedRetrospective StudiesAntineoplastic Agentschemoembolizationcollateral circulationcone-beam computed tomographyhepatocellular carcinomatherapeutic

Identifiers

PMID33235441
PMCPMC7680099
OpenAlexW3101856357

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.