Evidence map›Paper›PMID 33235395›Full record

ArticleMonatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde2021

[Prevalence of SARS-CoV-2 in children from a cohort of 2192 patients].

M Meyer, E Rübsteck, C Lehmann, F Klein, H Gruell, C Hünseler, L T Weber

Abstract readEnglish Abstract
In one paragraph

Article in Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

M MeyerMedizinische Fakultät und Uniklinik Köln, Klinik und Poliklinik für Kinder- und Jugendmedizin, Universität zu Köln, Kerpener Str. 62, 50924 Köln, Deutschland.
E RübsteckMedizinische Fakultät und Uniklinik Köln, Klinik und Poliklinik für Kinder- und Jugendmedizin, Universität zu Köln, Kerpener Str. 62, 50924 Köln, Deutschland.
C LehmannMedizinische Fakultät und Uniklinik Köln, Innere Medizin I (Onkologie, Hämatologie, Klinische Infektiologie, Klinische Immunologie, Hämostaseologie, Internistische Intensivmedizin), Universität zu Köln, Köln, Deutschland.
F KleinMedizinische Fakultät und Uniklinik Köln, Institut für Virologie, Universität zu Köln, Köln, Deutschland.
H GruellMedizinische Fakultät und Uniklinik Köln, Institut für Virologie, Universität zu Köln, Köln, Deutschland.
C HünselerMedizinische Fakultät und Uniklinik Köln, Klinik und Poliklinik für Kinder- und Jugendmedizin, Universität zu Köln, Kerpener Str. 62, 50924 Köln, Deutschland.
L T WeberMedizinische Fakultät und Uniklinik Köln, Klinik und Poliklinik für Kinder- und Jugendmedizin, Universität zu Köln, Kerpener Str. 62, 50924 Köln, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAs of 18 June 2020 a total of 187,764 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections were reported in Germany and of these 6.9% were under the age of 19 years. There were initial indications that children are often asymptomatic and show a milder clinical course.

objectiveThe aim of this study was to gain information on the prevalence of SARS-CoV‑2 infections in a pediatric cohort. MATERIAL AND

methodsBetween 13 March and 18 June 2020 all children from whom a smear for SARS-CoV‑2 was taken either to rule out an infection or as a suspected case were included. Data were collected on standardized patient record sheets. The analysis of data was anonymized and retrospective.

resultsDuring the given period 2192 children were investigated and 37 patients tested positive (1.7%) for SARS-CoV‑2. Of these 36/37 were suspected cases and 28/37 were symptomatic. The leading symptoms were dry cough, runny nose and fever and three children had to be hospitalized. None showed a difficult course of the disease. Among those tested 505 were patients at risk due to an underlying chronic disease, 3 of whom (0.6%) were tested positive with an asymptomatic or mild course.

conclusionWe can confirm the first data showing that children and adolescents often have an asymptomatic or mild clinical course of infection or disease. We found no evidence of a high grey area of SARS-CoV‑2 infections in this regional pediatric cohort.

Indexed as

COVID-19Dark figuresGermanyPatients at riskSymptoms

Identifiers

PMID33235395
PMCPMC7676857

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.