Evidence map›Paper›PMID 33235085›Full record

ArticleMedicine2020

Quantifying alcohol use among Ecuadorian human immunodeficiency virus positive individuals and assessing alcohol as an independent risk factor for human immunodeficiency virus: A case control study STROBE.

Jeffrey M Downen, Briana Swendener, Adriana A Bodlak, Diego F Añazco, Bryan I Nicolalde, Rahul Mhaskar, Nelson Cevallos, Alberto Castillo, David Larreategui, Edmundo Torres and 2 more

Abstract readMulticenter Study
In one paragraph

Article in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. HIV and Substance Use in Latin America: A Scoping Review.International journal of environmental research and public health · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jeffrey M DownenUniversity of South Florida Morsani College of Medicine, Tampa, Florida, United States.
Briana SwendenerUniversity of South Florida Morsani College of Medicine, Tampa, Florida, United States.
Adriana A BodlakUniversity of South Florida Morsani College of Medicine, Tampa, Florida, United States.
Diego F AñazcoUniversidad San Francisco de Quito Colegio de Ciencias de la Salud.
Bryan I NicolaldeUniversidad San Francisco de Quito Colegio de Ciencias de la Salud.
Rahul MhaskarUniversity of South Florida Morsani College of Medicine, Tampa, Florida, United States.
Nelson CevallosMinisterio de Salud Publica del Ecuador, Hospital Enrique Garces.
Alberto CastilloMinisterio de Salud Publica del Ecuador, Hospital Eugenio Espejo.
David LarreateguiInstituto Ecuatoriano de Seguridad Social, Hospital Carlos Andrade Marin, Quito, Ecuador.
Edmundo TorresInstituto Ecuatoriano de Seguridad Social, Hospital Carlos Andrade Marin, Quito, Ecuador.
Ricardo IzurietaUniversity of South Florida Morsani College of Medicine, Tampa, Florida, United States.
Enrique TeranUniversidad San Francisco de Quito Colegio de Ciencias de la Salud.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alcohol abuse has been identified as a risk factor for contracting human immunodeficiency virus (HIV) and accelerating disease progression. Our study aims to determine alcohol consumption rates among Ecuadorian HIV positive (HIV+) patients prior to diagnosis to evaluate its impact as an independent risk factor for contracting HIV. Additionally, we will examine post-diagnosis consumption rates among the HIV+ population.We provided anonymous questionnaires to 300 HIV+ patients and 600 internal medicine patients at 3 hospitals in Quito, Ecuador. Questionnaires quantified alcohol usage prior to HIV diagnosis, at time of diagnosis, and post-diagnosis while accounting for other potential HIV risk factors. We then determined frequencies of alcohol consumption and confounding variables. Finally, we performed a multivariable logistic regression controlling for confounders to determine the statistical significance of alcohol consumption as an independent risk factor for HIV.Our results showed increased odds for contracting HIV among those who drank daily (OR 5.3, CI 2.0-14.0) and those who consumed 6 or more alcoholic beverages on days they drank (OR 5.0, CI 3.1-8.2). Through multivariable analysis, we found that abstaining from binge drinking was a protective factor with an OR 0.5 (0.3-0.96). The percentage of HIV+ patients abstaining from alcohol increased from 30% twelve months prior to diagnosis to 57% after diagnosis.Our results show that alcohol abuse significantly increases the risk of contracting HIV. We found that prior to diagnosis, HIV patients consistently drank more frequently and a greater amount than the control group. Alcohol use significantly decreased among HIV+ patients after diagnosis.

Indexed as

AdultAlcohol DrinkingAlcoholismCase-Control StudiesDisease ProgressionEcuadorFemaleHIV InfectionsHIV SeropositivityHumansMaleMiddle AgedRisk Factors

Identifiers

PMID33235085
PMCPMC7710261

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.