Evidence map›Paper›PMID 33234971›Full record

ArticlePlastic and reconstructive surgery2020

Short-Term Outcomes following Virtual Surgery-Assisted Immediate Dental Implant Placement in Free Fibula Flaps for Oncologic Mandibular Reconstruction.

Robert J Allen, Jonas A Nelson, Thais O Polanco, Meghana G Shamsunder, Ian Ganly, Jay Boyle, Evan Rosen, Evan Matros

Abstract read
In one paragraph

Article in Plastic and reconstructive surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Robot-assisted jaw-in-a-day based on the sandwich approach: case series.Maxillofacial plastic and reconstructive surgery · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Robert J AllenFrom the Department of Surgery, Plastic and Reconstructive Surgery Service, Head and Neck Surgery Service, and Dental Service, Memorial Sloan Kettering Cancer Center.
Jonas A NelsonFrom the Department of Surgery, Plastic and Reconstructive Surgery Service, Head and Neck Surgery Service, and Dental Service, Memorial Sloan Kettering Cancer Center.
Thais O PolancoFrom the Department of Surgery, Plastic and Reconstructive Surgery Service, Head and Neck Surgery Service, and Dental Service, Memorial Sloan Kettering Cancer Center.
Meghana G ShamsunderFrom the Department of Surgery, Plastic and Reconstructive Surgery Service, Head and Neck Surgery Service, and Dental Service, Memorial Sloan Kettering Cancer Center.
Ian GanlyFrom the Department of Surgery, Plastic and Reconstructive Surgery Service, Head and Neck Surgery Service, and Dental Service, Memorial Sloan Kettering Cancer Center.
Jay BoyleFrom the Department of Surgery, Plastic and Reconstructive Surgery Service, Head and Neck Surgery Service, and Dental Service, Memorial Sloan Kettering Cancer Center.
Evan RosenFrom the Department of Surgery, Plastic and Reconstructive Surgery Service, Head and Neck Surgery Service, and Dental Service, Memorial Sloan Kettering Cancer Center.
Evan MatrosFrom the Department of Surgery, Plastic and Reconstructive Surgery Service, Head and Neck Surgery Service, and Dental Service, Memorial Sloan Kettering Cancer Center.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Elisa de Stanchina · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

backgroundDespite reports demonstrating feasibility of immediate dental implant placement in mandibular reconstruction with free fibula flaps for benign disease, this practice is not routinely used in the oncologic setting. The authors aim to demonstrate the safety of immediate dental implant placement for oncologic mandible reconstruction.

methodsIn 2017, the authors' center began immediate dental implant placement in free fibula flaps for oncologic patients undergoing mandibulectomy reconstruction. Immediate dental implant placement patients were compared to a historical cohort also reconstructed with computer-aided design and manufacturing technology beginning in 2011 (n = 34) as a noninferiority study design. Primary outcomes of interest included 90-day complications, time to radiotherapy, and time to and number of patients achieving dental restoration.

resultsSixty-one patients underwent free fibula flaps following mandibulectomy using computer-aided design and manufacturing. Seventy-two dental implants were placed in the immediate dental implant placement cohort (n = 27). No differences were noted in major or minor 90-day complications between groups (p > 0.05). Radiotherapy was required in 55 percent in the immediate dental implant placement cohort versus 62 percent in the historical cohort, with no significant difference in time to radiotherapy (67.6 days versus 62.2 days, respectively). One dental implant was removed for nonosseointegration noted during vestibuloplasty. Fourteen (51.8 percent) immediate dental implant patients had complete dental restoration at 90 days compared with none in the historical cohort (p < 0.05).

conclusionsImmediate dental implant placement is a safe procedure with an unchanged short-term complication profile and no delay in radiotherapy initiation. Patients undergoing immediate dental implant placement are more likely to complete full dental rehabilitation. Long-term and health-related quality-of-life outcomes remain to be determined. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, III.

Indexed as

AdultAgedBone TransplantationComputer-Aided DesignDental ImplantationDental ImplantsFemaleFibulaFree Tissue FlapsHumansMaleMandibleMandibular NeoplasmsMandibular OsteotomyMandibular ReconstructionMiddle AgedDental Implants

Identifiers

PMID33234971
PMCPMC7737649

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.