Evidence map›Paper›PMID 33234711›Full record

ArticleOpen heart2020

Clinical profile and prognostic factors of alcoholic cardiomyopathy in tribal and non-tribal population.

Ajit Dundung, Abhinav Kumar, Rishi Tuhin Guria, Mukul Preetam, Ruth K Tara, Bindey Kumar, Mohammad Kamal Saba

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Open heart, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Alcoholic cardiomyopathy: an update.European heart journal · 2024
    Review
  3. Review
  4. Alcohol and Heart Failure.European cardiology · 2023
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ajit DundungMedicine, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India.ORCID 0000-0001-6785-7277
Abhinav KumarMedicine, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India drshanki.avi@gmail.com.ORCID 0000-0002-5921-4359
Rishi Tuhin GuriaMedicine, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India.
Mukul PreetamMedicine, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India.
Ruth K TaraMedicine, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India.
Bindey KumarMedicine, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India.
Mohammad Kamal SabaMedicine, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India.
Rajendra Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAlcoholic cardiomyopathy (ACM) is a leading cause of non-ischaemic dilated cardiomyopathy (DCM) in tribal and non-tribal population. However, no study has been done depicting the correlation between clinical profile and prognosis of ACM in tribal and non-tribal population. This study also defines the long-term outcome and prognostic markers of ACM.

methodsWe studied 290 patients with ACM who were evaluated in our institute between January 2013 and December 2016. The primary endpoint of the study was all-cause mortality. Statistical analysis was done by using Kaplan-Meier survival curves for the assessment of all-cause mortality and Cox regression for the assessment of risk factors.

resultsAfter a median follow-up period of 3.75 years (IQR: 3-4 years), 50 patients with ACM (37.3%) died among tribal population while 14 patients (9%) died among non-tribal population. Independent predictors of all-cause mortality in ACM identified by Cox regression were left ventricular ejection fraction (LVEF) (HR: 0.883; 95% CI 0.783 to 0.996; p=0.043), QRS duration (HR: 1.010; 95% CI 1.007 to 1.017; p=0.005) and Child-Turcotte-Pugh (CTP) Scoring (HR: 12.332; 95% CI 6.999 to 21.728; p<0.001) at admission. The Kaplan-Meier survival probability estimate was 95.1% at 1 year and all-cause mortality was found to be higher in patients with QRS>120 ms, LVEF ≤35%, CTP Grade B/C than patients with QRS≤120 ms, LVEF >35% and CTP Score A, respectively (log-rank χ²=55.088, p<0.001; log-rank χ²=32.953, p<0.001; log-rank χ²=139.764, p<0.001, respectively).

conclusionOur study indicated increased morbidity and mortality in tribal population. LVEF, QRS duration and CTP Scoring at the time of presentation were found to be the independent prognostic markers of patients with ACM.

Indexed as

ElectrocardiographyAdultCardiomyopathy, AlcoholicDeath, Sudden, CardiacFemaleFollow-Up StudiesHumansIncidenceIndiaMaleMiddle AgedPrognosisRetrospective StudiesRisk FactorsStroke VolumeSurvival Ratecardiomyopathycommunity cardiologyprimary care

Identifiers

PMID33234711
PMCPMC7689074
OpenAlexW3106847244

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.