Evidence map›Paper›PMID 33234677›Full record

ArticleLife science alliance2021

G-CSF shifts erythropoiesis from bone marrow into spleen in the setting of systemic inflammation.

Weiqiang Jing, Xing Guo, Fei Qin, Yue Li, Ganyu Wang, Yuxuan Bi, Xing Jin, Lihui Han, Xiaoyuan Dong, Yunxue Zhao

Open access · goldAbstract read
In one paragraph

Article in Life science alliance, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 11 citations in OpenAlex.

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  5. Molecules (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Weiqiang JingDepartment of Pharmacology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, China.
Xing GuoDepartment of Pharmacology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, China.
Fei QinDepartment of Pharmacology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, China.
Yue LiDepartment of Pharmacology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, China.
Ganyu WangDepartment of Pharmacology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, China.
Yuxuan BiDepartment of Pharmacology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, China.
Xing JinDepartment of Pharmacology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, China.
Lihui HanDepartment of Immunology, Shandong Key Laboratory of Infection and Immunity, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, China.
Xiaoyuan DongDepartment of Hematology, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Yunxue ZhaoDepartment of Pharmacology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, China zhaoyunxue@sdu.edu.cn.ORCID 0000-0003-3670-9436
Shandong University · CNQilu Hospital of Shandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The anemia of inflammation is related in part to abnormal erythropoiesis in bone marrow. G-CSF regulates granulopoiesis and is increased during systemic inflammation. Here, we have showed that high levels of G-CSF are associated with repression of bone marrow erythropoiesis and expansion of splenic erythropoiesis in

Indexed as

AnimalsBone MarrowErythropoiesisErythropoietinEscherichia coliEscherichia coli InfectionsGranulocyte Colony-Stimulating FactorInjections, SubcutaneousLipopolysaccharidesMiceMice, Inbred C57BLMice, KnockoutSignal TransductionSpleenSystemic Inflammatory Response SyndromeToll-Like Receptor 4Epo protein, mouseErythropoietinGranulocyte Colony-Stimulating FactorLipopolysaccharidesTlr4 protein, mouseToll-Like Receptor 4

Identifiers

PMID33234677
PMCPMC7723243
OpenAlexW3107876815

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.