Evidence map›Paper›PMID 33234627›Full record

ArticleBMJ open2020

Strategies for enhancing the initiation of cholesterol lowering medication among patients at high cardiovascular disease risk: a qualitative descriptive exploration of patient and general practitioners' perspectives on a facilitated relay intervention in Alberta, Canada.

David J T Campbell, Rachelle C W Lee-Krueger, Kerry McBrien, Todd Anderson, Hude Quan, Alexander A Leung, Guanmin Chen, Mingshan Lu, Christopher Naugler, Sonia Butalia

Registry-linked trialAbstract read
In one paragraph

Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07280325 (Moxie), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07280325 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Moxie: A Self-management Education and Support Program Using Advertising Principles to Reduce Rehospitalization for Cardiovascular-related Illnesses

TypeinterventionalSponsorUniversity of CalgaryRan2026 to 2029Enrolled9,000ConditionsChronic Kidney Disease, Diabetes (DM), Heart Disease, StrokeArmsMoxie SMES Letters, Facilitated Relay Letter
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

David J T CampbellDepartment of Medicine, University of Calgary Cumming School of Medicine, Calgary, Alberta, Canada dcampbel@ucalgary.ca.ORCID 0000-0002-5570-3630
Rachelle C W Lee-KruegerDepartment of Innovation in Medical Education, University of Ottawa, Ottawa, Ontario, Canada.
Kerry McBrienDepartment of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0003-3761-237X
Todd AndersonDepartment of Cardiac Sciences, University of Calgary Cumming School of Medicine, Calgary, Alberta, Canada.
Hude QuanDepartment of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
Alexander A LeungDepartment of Medicine, University of Calgary Cumming School of Medicine, Calgary, Alberta, Canada.
Guanmin ChenDepartment of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
Mingshan LuDepartment of Economics, University of Calgary, Calgary, Alberta, Canada.
Christopher NauglerDepartment of Pathology & Laboratory Medicine, University of Calgary, Calgary, Alberta, Canada.
Sonia ButaliaDepartment of Medicine, University of Calgary Cumming School of Medicine, Calgary, Alberta, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe objective of our study was to explore the perspectives of patients and general practitioners (GPs) regarding interventions to increase initiation of cholesterol lowering medication (or statins), including a proposed laboratory-based facilitated relay intervention.

designQualitative descriptive study using interviews and focus groups for data collection, and thematic analysis for data analysis.

settingPrimary care providers and patients in Calgary, Alberta, Canada.

participants17 GPs with primarily community-based, non-academic practices with at least 1 year of practice experience participated in semistructured interviews. 14 patients at high risk of cardiovascular disease participated in focus groups.

main outcome measuresExploration of strategies that might be used to enhance the prescription of, and adherence to statin therapy for patients with statin-indicated conditions.

resultsGPs proposed a variety of interventions to improve statin prescription, including electronic record audit solutions, GP directed education, and patient-oriented campaigns. Patients expressed that they may benefit from being provided access to their laboratory test results, as well as targeted education. Both parties provided positive feedback on the proposed laboratory-based facilitated relay intervention, while pointing out areas for improvement. Notably, GPs were concerned that the patient-directed component of the intervention might jeopardise therapeutic relationships, and patients were concerned about accidental disclosure of personal health information. Important considerations for the design of facilitated relay messaging should include brevity, simplicity and the provision of contact information for inquiries.

conclusionsGPs and patients described several suggestions for increasing statin initiation and welcomed the proposal of a laboratory-based facilitated relay strategy. These findings support further testing of this intervention which may enhance GPs' ability to successfully engage patients in cardiovascular risk reduction through statin therapy.

Indexed as

Cardiovascular DiseasesGeneral PractitionersAgedAlbertaAttitude of Health PersonnelCholesterolFemaleHumansMaleQualitative ResearchCholesterolcardiologygeneral medicine (see internal medicine)preventive medicinequalitative researchquality in health care

Identifiers

PMID33234627
PMCPMC7689086

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.