Evidence map›Paper›PMID 33234612›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2021

Impaired θ-γ Coupling Indicates Inhibitory Dysfunction and Seizure Risk in a Dravet Syndrome Mouse Model.

Nico A Jansen, Carlos Perez, Maarten Schenke, Anouk W van Beurden, Anisa Dehghani, Rob A Voskuyl, Roland D Thijs, Ghanim Ullah, Arn M J M van den Maagdenberg, Else A Tolner

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
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  8. Distinct ACC Neural Mechanisms Underlie Authentic and Transmitted Anxiety Induced by Maternal Separation in Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  9. [Alterations of β-γ coupling of scalp electroencephalography during epilepsy].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2023
    Article
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  18. DecipheringFrontiers in cellular neuroscience · 2021
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Nico A JansenDepartment of Human Genetics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands n.a.jansen@lumc.nl.ORCID 0000-0001-9905-054X
Carlos PerezDepartment of Physics, University of South Florida, Tampa, Florida 33620.
Maarten SchenkeDepartment of Human Genetics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
Anouk W van BeurdenDepartment of Human Genetics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.ORCID 0000-0002-0551-0347
Anisa DehghaniDepartment of Human Genetics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.ORCID 0000-0002-7117-4599
Rob A VoskuylDepartment of Human Genetics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.
Roland D ThijsDepartment of Neurology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.ORCID 0000-0003-1435-8970
Ghanim UllahDepartment of Physics, University of South Florida, Tampa, Florida 33620.ORCID 0000-0002-3716-8742
Arn M J M van den MaagdenbergDepartment of Human Genetics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.ORCID 0000-0002-9310-5535
Else A TolnerDepartment of Human Genetics, Leiden University Medical Center, 2300 RC Leiden, The Netherlands.ORCID 0000-0002-6501-9971
Leiden University Medical Center · NLUniversity of South Florida · US

Funding

A multi-scale data-driven model of the Abeta pore function and Ca2+ toxicity in Alzheimer's diseaseR01AG053988 · NIA · UNIVERSITY OF SOUTH FLORIDA · PI DEMURO, ANGELO, ULLAH, GHANIM · 2016 to 2020
$2.1M
NIA NIH HHS R01 AG053988
6 · The paper itself

Abstract

Dravet syndrome (DS) is an epileptic encephalopathy that still lacks biomarkers for epileptogenesis and its treatment. Dysfunction of Na

Indexed as

Gamma RhythmTheta RhythmAnimalsAnticonvulsantsBiomarkersCannabidiolCerebral CortexComputer SimulationElectroencephalographyEpilepsies, MyoclonicEpilepsyFemaleHippocampusInterneuronsMaleMiceAnticonvulsantsBiomarkersCannabidiolNAV1.1 Voltage-Gated Sodium ChannelPotassium Channels, Voltage-GatedScn1a protein, mouseDravet syndromeepilepsyinterneuronsNav1.1sodium channels

Identifiers

PMID33234612
PMCPMC7821857
OpenAlexW3110512604

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.