Evidence map›Paper›PMID 33234610›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2021

Brain-Derived Neurotrophic Factor/Tropomyosin Receptor Kinase B Signaling Controls Excitability and Long-Term Depression in Oval Nucleus of the BNST.

Dominik Fiedler, Manju Sasi, Robert Blum, Christopher M Klinke, Marta Andreatta, Hans-Christian Pape, Maren D Lange

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Cordycepin alleviates nicotine withdrawal-induced anxietyDrug and alcohol dependence reports · 2026
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  6. HumanFrontiers in neuroscience · 2025
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  7. Genetic Predisposition and Severity of Eating Disorders- A Review.CNS & neurological disorders drug targets · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Dominik FiedlerInstitute of Physiology I, Westfälische Wilhelms-University Münster, 48149 Münster, Germany.
Manju SasiInstitute of Clinical Neurobiology, University Hospital Würzburg, 97078 Würzburg, Germany.
Robert BlumInstitute of Clinical Neurobiology, University Hospital Würzburg, 97078 Würzburg, Germany.ORCID 0000-0002-5270-3854
Christopher M KlinkeDepartment of Biological Psychology, Clinical Psychology and Psychotheraphy, Julius-Maximilians-University Würzburg, 97070 Würzburg, Germany.
Marta AndreattaDepartment of Biological Psychology, Clinical Psychology and Psychotheraphy, Julius-Maximilians-University Würzburg, 97070 Würzburg, Germany.ORCID 0000-0002-1217-8266
Hans-Christian PapeInstitute of Physiology I, Westfälische Wilhelms-University Münster, 48149 Münster, Germany.
Maren D LangeInstitute of Physiology I, Westfälische Wilhelms-University Münster, 48149 Münster, Germany m.lange@uni-muenster.de.
University of Münster · DEUniversitätsklinikum Würzburg · DEUniversity of Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dysregulation of proteins involved in synaptic plasticity is associated with pathologies in the CNS, including psychiatric disorders. The bed nucleus of the stria terminalis (BNST), a brain region of the extended amygdala circuit, has been identified as the critical hub responsible for fear responses related to stress coping and pathologic systems states. Here, we report that one particular nucleus, the oval nucleus of the BNST (ovBNST), is rich in brain-derived neurotrophic factor (BDNF) and tropomyosin receptor kinase B (TrkB) receptor. Whole-cell patch-clamp recordings of neurons from male mouse ovBNST

Indexed as

AnimalsBrain-Derived Neurotrophic FactorLong-Term Synaptic DepressionMaleMembrane GlycoproteinsMembrane PotentialsMiceMice, Inbred C57BLPatch-Clamp TechniquesPotassium Channels, Inwardly RectifyingProtein-Tyrosine KinasesReceptor, trkBSeptal NucleiStress, PsychologicalSynapsesSynaptic TransmissionBdnf protein, mouseBrain-Derived Neurotrophic FactorMembrane GlycoproteinsNtrk2 protein, mousePotassium Channels, Inwardly RectifyingProtein-Tyrosine KinasesReceptor, trkBBDNFBNSTfearLTDstressTrkB

Identifiers

PMID33234610
PMCPMC7821854
OpenAlexW3110330641

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.