Evidence map›Paper›PMID 33234608›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2021

Enhancing GABAergic Tone in the Rostral Nucleus of the Solitary Tract Reconfigures Sensorimotor Neural Activity.

Joshua D Sammons, Caroline E Bass, Jonathan D Victor, Patricia M Di Lorenzo

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Joshua D SammonsDepartment of Psychology, Binghamton University, Binghamton, New York 13902-6000.
Caroline E BassDepartment of Pharmacology and Toxicology, Jacobs School of Medicine and Biomedical Sciences, Buffalo, New York 14203.
Jonathan D VictorFeil Family Brain and Mind Research Institute, Weill Cornell Medical College, New York, New York 10065.
Patricia M Di LorenzoDepartment of Psychology, Binghamton University, Binghamton, New York 13902-6000 diloren@binghamton.edu.
Binghamton University · USJacobs Institute · USMIND Research Institute · US

Funding

Temporal Coding in the Gustatory System of the BrainR01DC006914 · NIDCD · STATE UNIVERSITY OF NY,BINGHAMTON · PI DI LORENZO, PATRICIA M · 2006 to 2020
$5.3M
Targeted chemogenetic stimulation of rat VTA GABA neurons in cocaine extinction and reinstatementR21DA043190 · NIDA · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI BASS, CAROLINE EVELYN · 2017 to 2018
$439k
NIDA NIH HHS R21 DA043190NIDCD NIH HHS R01 DC006914
6 · The paper itself

Abstract

Recent work has shown that most cells in the rostral, gustatory portion of the nucleus tractus solitarius (rNTS) in awake, freely licking rats show lick-related firing. However, the relationship between taste-related and lick-related activity in rNTS remains unclear. Here, we tested whether GABA-derived inhibitory activity regulates the balance of lick- and taste-driven neuronal activity. Combinatorial viral tools were used to restrict the expression of channelrhodopsin 2-enhanced yellow fluorescent protein to GAD1

Indexed as

AnimalsElectrodes, ImplantedElectrophysiological PhenomenaFemaleFluorescent Dyesgamma-Aminobutyric AcidGlutamate DecarboxylaseMaleMotor ActivityPhotic StimulationRatsRats, Sprague-DawleySensationSolitary NucleusTasteTaste PerceptionFluorescent Dyesgamma-Aminobutyric AcidGlutamate Decarboxylaseglutamate decarboxylase 1brainstemGABAgustatoryneural codingnucleus of the solitary tracttaste

Identifiers

PMID33234608
PMCPMC7821855
OpenAlexW3106735042

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.