Evidence map›Paper›PMID 33234583›Full record

ArticleCMAJ open

Health service use among Manitobans with alcohol use disorder: a population-based matched cohort study.

James M Bolton, Christine Leong, Okechukwu Ekuma, Heather J Prior, Geoffrey Konrad, Jennifer Enns, Deepa Singal, Josh Nepon, Michael T Paillé, Greg Finlayson and 1 more

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in CMAJ open. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05375682 (Integrating Care for Patients With Alcohol Liver Disease and Mental Health and Alcohol Use Disorders), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05375682 nacompletednot on this map

Integrating Care for Patients With Alcohol Liver Disease and Mental Health and Alcohol Use Disorders: A Pilot Study

TypeinterventionalSponsorUniversity of ManitobaRan2024 to 2026Enrolled30ConditionsAlcohol, LiverArmsIntegrated care program
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

James M BoltonDepartment of Psychiatry (Bolton, Leong, Konrad, Nepon), Manitoba Centre for Health Policy (Bolton, Ekuma, Prior, Enns, Singal, Paillé, Finlayson, Nickel), College of Pharmacy (Leong) and Department of Community Health Sciences (Nickel), Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Man.
Christine LeongDepartment of Psychiatry (Bolton, Leong, Konrad, Nepon), Manitoba Centre for Health Policy (Bolton, Ekuma, Prior, Enns, Singal, Paillé, Finlayson, Nickel), College of Pharmacy (Leong) and Department of Community Health Sciences (Nickel), Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Man.
Okechukwu EkumaDepartment of Psychiatry (Bolton, Leong, Konrad, Nepon), Manitoba Centre for Health Policy (Bolton, Ekuma, Prior, Enns, Singal, Paillé, Finlayson, Nickel), College of Pharmacy (Leong) and Department of Community Health Sciences (Nickel), Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Man.
Heather J PriorDepartment of Psychiatry (Bolton, Leong, Konrad, Nepon), Manitoba Centre for Health Policy (Bolton, Ekuma, Prior, Enns, Singal, Paillé, Finlayson, Nickel), College of Pharmacy (Leong) and Department of Community Health Sciences (Nickel), Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Man.
Geoffrey KonradDepartment of Psychiatry (Bolton, Leong, Konrad, Nepon), Manitoba Centre for Health Policy (Bolton, Ekuma, Prior, Enns, Singal, Paillé, Finlayson, Nickel), College of Pharmacy (Leong) and Department of Community Health Sciences (Nickel), Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Man.
Jennifer EnnsDepartment of Psychiatry (Bolton, Leong, Konrad, Nepon), Manitoba Centre for Health Policy (Bolton, Ekuma, Prior, Enns, Singal, Paillé, Finlayson, Nickel), College of Pharmacy (Leong) and Department of Community Health Sciences (Nickel), Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Man.
Deepa SingalDepartment of Psychiatry (Bolton, Leong, Konrad, Nepon), Manitoba Centre for Health Policy (Bolton, Ekuma, Prior, Enns, Singal, Paillé, Finlayson, Nickel), College of Pharmacy (Leong) and Department of Community Health Sciences (Nickel), Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Man.
Josh NeponDepartment of Psychiatry (Bolton, Leong, Konrad, Nepon), Manitoba Centre for Health Policy (Bolton, Ekuma, Prior, Enns, Singal, Paillé, Finlayson, Nickel), College of Pharmacy (Leong) and Department of Community Health Sciences (Nickel), Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Man.
Michael T PailléDepartment of Psychiatry (Bolton, Leong, Konrad, Nepon), Manitoba Centre for Health Policy (Bolton, Ekuma, Prior, Enns, Singal, Paillé, Finlayson, Nickel), College of Pharmacy (Leong) and Department of Community Health Sciences (Nickel), Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Man.
Greg FinlaysonDepartment of Psychiatry (Bolton, Leong, Konrad, Nepon), Manitoba Centre for Health Policy (Bolton, Ekuma, Prior, Enns, Singal, Paillé, Finlayson, Nickel), College of Pharmacy (Leong) and Department of Community Health Sciences (Nickel), Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Man.
Nathan C NickelDepartment of Psychiatry (Bolton, Leong, Konrad, Nepon), Manitoba Centre for Health Policy (Bolton, Ekuma, Prior, Enns, Singal, Paillé, Finlayson, Nickel), College of Pharmacy (Leong) and Department of Community Health Sciences (Nickel), Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Man. Nathan_Nickel@umanitoba.ca.
Manitoba Health · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlcohol is the drug most commonly used by Canadians, with multiple impacts on health and health service use. We examined patterns of short- and long-term health service use among people with a diagnosis of alcohol use disorder.

methodsIn this retrospective matched cohort study, we used population-based administrative data from the province of Manitoba, Canada, to identify individuals aged 12 years or older with a first indication of alcohol use disorder (index date) in the period 1990 to 2015. We matched cases (those with diagnosis of alcohol use disorder) to controls (those without this diagnosis), at a 1:5 ratio, on the basis of age, sex, geographic region and income quintile at the index date. The outcome measures were inpatient hospital admission, outpatient physician visits, emergency department visits and use of prescription medications. We modelled crude rates using generalized estimating equations with either a negative binomial or a Poisson distribution

resultsWe identified 53 410 people with alcohol use disorder and 264 857 matched controls. All outcomes occurred at a higher rate among people with the disorder than among controls. For example, during the year of diagnosis, the rate ratio for hospital admission was 4.0 (95% confidence interval [CI] 3.9-4.2) for women and 4.5 (95% CI 4.4-4.7) for men. All rates of health service use peaked close to the index date, but remained significantly higher among people with alcohol use disorder than among controls for 20 years. Among people with alcohol use disorder, the most commonly filled prescriptions were for psycholeptics, whereas among controls, the most commonly filled prescriptions were for sex hormones (women) and antihypertensives (men).

interpretationCompared with controls, people with alcohol use disorder used significantly more health services from the time of diagnosis and over the next 20 years. This finding highlights the need for better detection and early intervention to reduce the need for acute and emergency care, as well as the need for improved management of alcohol use disorder over the longer term.

Indexed as

AdolescentAdultAgedAged, 80 and overAge DistributionAlcohol-Related DisordersChildFemaleHospitalizationHumansMaleManitobaMiddle AgedPatient Acceptance of Health CareRetrospective StudiesSex Distribution

Identifiers

PMID33234583
PMCPMC7721253
OpenAlexW3108493431

What OpenQuestion holds

Textmetadata
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.