ArticleBJGP open2021
Treatment of uncomplicated UTI in males: a systematic review of the literature.
Article in BJGP open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
20 citing papers in PubMed, 25 citations in OpenAlex.
- Uncomplicated Urinary Tract Infections: From an Invisible Impact to a Visible Change in Complex Care.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026Article
- Comprehensive Evaluation of Uropathogens' AMR in a Romanian Tertiary Center: Male vs. Female Comparison.Microorganisms · 2026Article
- Comparative Analysis of Antimicrobial Resistance in Male Uropathogens Before and After the COVID-19 Pandemic: A Single-Center Study from Romania.Medicina (Kaunas, Lithuania) · 2026Article
- Antimicrobial resistance in ESKAPEE pathogens isolated from institutionalized vs. non-institutionalized elderly patients with urinary tract infections: a 5-years study.World journal of urology · 2026Observational
- Diagnostic tests for urinary tract infections and antimicrobial resistance-a reality check between diagnostic innovation and implementation: a critical narrative review.Frontiers in cellular and infection microbiology · 2026Review
- Infrared Spectroscopic Profiling of Volatile Metabolites from Uropathogenic Bacteria: Basic Investigations toward Rapid UTI Diagnostics.Analytical chemistry · 2025Article
- Risk factors for poor prognosis in adult outpatient urinary tract infection: a meta-analysis.BJGP open · 2025Article
- Article
- Bacterial growth and antimicrobial resistance in urinaryJAC-antimicrobial resistance · 2025Article
- Less is more: the lack of autoinducer-2-dependent quorum sensing promotes competitive fitness ofFrontiers in cellular and infection microbiology · 2025Article
- Short-course intravenous beta-lactams for uncomplicated cystitis in hospitalized patients.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
- Public Interest in Online Information on Recurrent Urinary Tract Infections Is Greatest for Information with the Poorest Publication Quality.Pathogens (Basel, Switzerland) · 2024Article
- GPs' experience with diagnosis and treatment guidelines for lower UTI in men: a qualitative interview.BJGP open · 2024Article
- Acute cystitis in men- a nationwide study from primary care: antibiotic prescriptions, risk factors, and complications.BJGP open · 2024Article
- Regional variations in antimicrobial susceptibility of community-acquired uropathogenicIJID regions · 2024Article
- Urinary Tract Infections in Men in Primary Care in Catalonia, Spain.Antibiotics (Basel, Switzerland) · 2023Article
- High antimicrobial resistance in urinary tract infections in male outpatients in routine laboratory data, Germany, 2015 to 2020.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2022Observational
- In vitro Studies of Non-DiphtheriaeInfection and drug resistance · 2022Article
- Clinical Efficacy and Cost Analysis of Antibiotics for Treatment of Uncomplicated Urinary Tract Infections in the Emergency Department of a Tertiary Hospital in Saudi Arabia.Therapeutics and clinical risk management · 2021Article
- Acute Cystitis in a Transfeminine Patient: Assessment and Treatment of Urinary Tract Symptoms.Journal of midwifery & women's healthArticle
Corrections and comments
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Authors and funding
10 authors at 8 institutions in 8 countries.
Funding
Abstract
backgroundUrinary tract infections (UTIs) affect around 20% of the male population in their lifetime. The incidence of UTIs in men in the community is 0.9-2.4 cases per 1000 aged <55 years and 7.7 per 1000 aged ≥85 years.
aimTo evaluate the outcomes of randomised controlled trials (RCTs) comparing the effectiveness of different antimicrobial treatments and durations for uncomplicated UTIs in adult males in outpatient settings.
methodA systematic literature review of RCTs of adult male patients with an uncomplicated UTI treated with oral antimicrobials in any outpatient setting. The outcomes were symptom resolution within 2 weeks of starting treatment, duration until symptom resolution, clinical cure, bacteriological cure, and frequency of adverse events.
resultsFrom the 1052 abstracts screened, three provided sufficient information on outcomes. One study compared trimethoprim-sulfamethoxazole for 14 days (21 males) with 42 days (21 males). Fluoroquinolones were compared in the two other RCTs: lomefloxacin (10 males) with norfloxacin (11 males), and ciprofloxacin for 7 days (19 males) and 14 days (19 males). Combining the results from the three RCTs shows that for 75% males with a UTI (76/101) bacteriological cure was reported at the end of the study. Of the 59 patients receiving a fluoroquinolone, 57 (97%) reported bacteriological and clinical cure within 2 weeks after treatment.
conclusionThe evidence available is insufficient to make any recommendations in relation to type and duration of antimicrobial treatment for male UTIs. Sufficiently powered RCTs are needed to identify best treatment type and duration for male UTIs in primary care.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.