ArticleBMC infectious diseases2020
Seroprevalence, spatial dispersion and factors associated with flavivirus and chikungunha infection in a risk area: a population-based seroprevalence study in Brazil.
Article in BMC infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Chikungunya seroprevalence in population-based studies: a systematic review and meta-analysis.Archives of public health = Archives belges de sante publique · 2023Pooled it
- Article
- Spatial epidemiology of dengue and chikungunya in Karnataka using GIS-based analysis.Global health action · 2025Article
- Seroprevalence of dengue, Zika, and chikungunya in São Sebastião, Brazil (2020-2021): a population-based survey.BMC infectious diseases · 2025Article
- High prevalence of dengue, Zika, and chikungunya viruses in blood donors during a dengue outbreak and an endemic period in Colombia.Frontiers in medicine · 2024Article
- High seroprevalence of antibodies against arboviruses in postpartum women in Salvador, Brazil.IJID regions · 2023Article
- Dynamics of chikungunya virus transmission in the first year after its introduction in Brazil: A cohort study in an urban community.PLoS neglected tropical diseases · 2023Article
- Seroprevalence of Dengue, Chikungunya and Zika at the epicenter of the congenital microcephaly epidemic in Northeast Brazil: A population-based survey.PLoS neglected tropical diseases · 2023Article
- Epidemiology and Economic Burden of Chikungunya: A Systematic Literature Review.Tropical medicine and infectious disease · 2023Review
- A Serosurvey of Japanese Encephalitis Virus in Monkeys and Humans Living in Proximity in Thailand.Viruses · 2023Article
- Peculiarities of Zika Immunity and Vaccine Development: Lessons from Dengue and the Contribution from Controlled Human Infection Model.Pathogens (Basel, Switzerland) · 2022Review
- Antecedent infections in Guillain-Barré syndrome in endemic areas of arbovirus transmission: A multinational case-control study.Journal of the peripheral nervous system : JPNS · 2021Observational
- Serological and molecular epidemiology of the Dengue, Zika and Chikungunya viruses in a risk area in Brazil.BMC infectious diseases · 2021Observational
- Dengue-2 and Guadeloupe Mosquito Virus RNA Detected inInsects · 2021Article
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14 authors at 5 institutions in 1 country.
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Abstract
backgroundThe State of Ceará, in Northeastern Brazil, suffers from a triple burden of arboviruses (dengue, Zika and chikungunya). We measured the seroprevalence of chikungunya, dengue and Zika and its associated factors in the population of Juazeiro do Norte, Southern Ceará State, Brazil.
methodsA cross-sectional study of analytical and spatial analysis was performed to estimate the seroprevalence of dengue, Zika and chikungunya, in the year 2018. Participants were tested for IgM and IgG against these three viruses. Those with IgM and/or IgG positive tests results were considered positive. Poisson regression was used to analyze the factors associated with positive cases, in the same way that the spatial analysis of positive cases was performed to verify whether the cases were grouped.
resultsOf the 404 participants, 25.0% (103/404) were positive for CHIKV, 92.0% (373/404) for flavivirus (dengue or Zika) and of these, 37.9% (153/404) samples were classified as probable dengue infection. Of those who reported having had an arbovirus in the past, positive CHIKV cases had 58.7% arthralgia (PR = 4.31; 95% CI: 2.06-9.03; p = 0.000) mainly in the hands, ankles and feet. Age over 60 years had a positive association with cases of flavivirus (PR = 1.29; 95% CI: 1.09-1.54; p = 0.000). Fever, muscle pain, joint pain and skin rash were the most reported symptoms (46.1, 41.0, 38.3 and 28.41%, respectively). The positive cases of chikungunya and dengue or Zika were grouped in space and the city center was most affected area.
conclusionsFour years after the introduction of CHIKV, where DENV has been in circulation for over 30 years, 1/4 of the population has already been exposed, showing the extent of the epidemic. The measured prevalence was much higher than that reported by local epidemiological surveillance.
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