Evidence map›Paper›PMID 33233863›Full record

ReviewJournal of clinical medicine2020

Impact of Air Pollution and Weather on Dry Eye.

Jordan T Mandell, Maria Idarraga, Naresh Kumar, Anat Galor

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jordan T MandellMiller School of Medicine, University of Miami, Miami, FL 33136, USA.
Maria IdarragaBascom Palmer Eye Institute, University of Miami, Miami, FL 33136, USA.ORCID 0000-0003-2421-9528
Naresh KumarEpidemiology and Public Health, University of Miami, Miami, FL 33136, USA.
Anat GalorBascom Palmer Eye Institute, University of Miami, Miami, FL 33136, USA.ORCID 0000-0002-3026-6155

Funding

Shared Equipment ModuleP30EY014801 · NEI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Victor L Perez · 2004 to 2026
$12.2M
Tear protein biomarkers of refractive surgery painR61EY032468 · NEI · OREGON HEALTH & SCIENCE UNIVERSITY · PI AICHER, SUE A, GALOR, ANAT · 2020 to 2022
$2.0M
Dry Eye and MicroenvironmentR01EY026174 · NEI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI GALOR, ANAT, KUMAR, NARESH · 2016 to 2020
$1.9M
Neural mechanisms underlying photophobia and dry eyeI01CX002015 · VA · MIAMI VA HEALTH CARE SYSTEM · PI Anat Galor · 2020 to 2026
–
and Biomedical Laboratory R&D (BLRD) BX004893CSRD VA I01 CX002015Department of Defense Gulf War Illness Research Program (GWIRP) W81XWH-20-1-0579NEI NIH HHS R01EY026174NEI NIH HHS R61EY032468NIH Center Core Grant P30EY014801Vision Research Program (VRP) W81XWH2010820
6 · The paper itself

Abstract

Air pollution has broad effects on human health involving many organ systems. The ocular surface is an excellent model with which to study the effects of air pollution on human health as it is in constant contact with the environment, and it is directly accessible, facilitating disease monitoring. Effects of air pollutants on the ocular surface typically manifest as dry eye (DE) symptoms and signs. In this review, we break down air pollution into particulate matter (organic and inorganic) and gaseous compounds and summarize the literature regarding effects of various exposures on DE. Additionally, we examine the effects of weather (relative humidity, temperature) on DE symptoms and signs. To do so, we conducted a PubMed search using key terms to summarize the existing literature on the effects of air pollution and weather on DE. While we tried to focus on the effect of specific exposures on specific aspects of DE, environmental conditions are often studied concomitantly, and thus, there are unavoidable interactions between our variables of interest. Overall, we found that air pollution and weather conditions have differential adverse effects on DE symptoms and signs. We discuss these findings and potential mitigation strategies, such as air purifiers, air humidifiers, and plants, that may be instituted as treatments at an individual level to address environmental contributors to DE.

Indexed as

air qualitydry eyeindoor air pollutionoutdoor air pollution

Identifiers

PMID33233863
PMCPMC7699870

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.