Evidence map›Paper›PMID 33233803›Full record

ArticleInternational journal of molecular sciences2020

A Potential Involvement of Anandamide in the Modulation of HO/NOS Systems: Women, Menopause, and "Medical Cannabinoids".

Renáta Szabó, Denise Börzsei, Zsuzsanna Szabó, Alexandra Hoffmann, István Zupkó, Dániel Priksz, Krisztina Kupai, Csaba Varga, Anikó Pósa

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Renáta SzabóDepartment of Physiology, Anatomy and Neuroscience, Faculty of Science and Informatics, University of Szeged, H-6726 Szeged, Hungary.
Denise BörzseiDepartment of Physiology, Anatomy and Neuroscience, Faculty of Science and Informatics, University of Szeged, H-6726 Szeged, Hungary.
Zsuzsanna SzabóDepartment of Physiology, Anatomy and Neuroscience, Faculty of Science and Informatics, University of Szeged, H-6726 Szeged, Hungary.
Alexandra HoffmannDepartment of Physiology, Anatomy and Neuroscience, Faculty of Science and Informatics, University of Szeged, H-6726 Szeged, Hungary.
István ZupkóDepartment of Pharmacodynamics and Biopharmacy, University of Szeged, H-6720 Szeged, Hungary.ORCID 0000-0003-3243-5300
Dániel PrikszDepartment of Pharmacology and Pharmacotherapy, Faculty of Medicine, University of Debrecen, H-4032 Debrecen, Hungary.ORCID 0000-0002-5818-4557
Krisztina KupaiDepartment of Physiology, Anatomy and Neuroscience, Faculty of Science and Informatics, University of Szeged, H-6726 Szeged, Hungary.
Csaba VargaDepartment of Physiology, Anatomy and Neuroscience, Faculty of Science and Informatics, University of Szeged, H-6726 Szeged, Hungary.
Anikó PósaDepartment of Physiology, Anatomy and Neuroscience, Faculty of Science and Informatics, University of Szeged, H-6726 Szeged, Hungary.
University of Szeged · HUUniversity of Debrecen · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endocannabinoids and their receptors are present in the cardiovascular system; however, their actions under different pathological conditions remain controversial. The aim of our study was to examine the effects of anandamide (AEA) on heme oxygenase (HO) and nitric oxide synthase (NOS) systems in an estrogen-depleted rat model. Sham-operated (SO) and surgically induced estrogen-deficient (OVX) female Wistar rats were used. During a two-week period, a group of OVX rats received 0.1 mg/kg estrogen (E

Indexed as

AnimalsArachidonic AcidsCalcitonin Gene-Related PeptideCannabinoid Receptor AgonistsEndocannabinoidsEstrogen Replacement TherapyEstrogensFemaleHeme Oxygenase (Decyclizing)HumansNitric Oxide Synthase Type IIIOvariectomyPolyunsaturated AlkamidesRatsRats, WistarReceptor, Cannabinoid, CB1anandamideArachidonic AcidsCalcitonin Gene-Related PeptideCannabinoid Receptor AgonistsCnr1 protein, ratEndocannabinoidsEstrogensHeme Oxygenase (Decyclizing)Nitric Oxide Synthase Type IIINos3 protein, ratPolyunsaturated AlkamidesReceptor, Cannabinoid, CB1Trpv1 protein, ratTRPV Cation Channelsanandamidecardiovascular systemheme oxygenasenitric oxide synthase

Identifiers

PMID33233803
PMCPMC7699915
OpenAlexW3100131503

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.