ReviewFoods (Basel, Switzerland)2020
Food Ingredients and Active Compounds against the Coronavirus Disease (COVID-19) Pandemic: A Comprehensive Review.
Review in Foods (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
75 citing papers in PubMed, 235 citations in OpenAlex.
- Food simulants affected the migration of essential oil and film structure in chitosan based composite films.Journal of food science and technology · 2025Article
- Grape seed extract and L-ascorbic acid exert antineoplastic effects against solid Ehrlich carcinomaFrontiers in immunology · 2025Article
- Resilience during lockdown: a longitudinal study investigating changes in behaviour and attitudes among older females during COVID-19 lockdown in the UK.BMC public health · 2024Article
- Optimization of the method of ultrasonic extraction of lycopene with a green extract from the fruit ofFood science & nutrition · 2024Article
- Innate Immune-Enhancing Effect ofJournal of microbiology and biotechnology · 2024Article
- Valorization of pineapple rind for bromelain extraction using microwave assisted technique: optimization, purification, and structural characterization.Journal of food science and technology · 2024Article
- Novel Electromagnetic Heat Hydrodistillation for Extraction of Essential Oil from Tangerine Peel.Foods (Basel, Switzerland) · 2024Article
- The Future of Food.Foods (Basel, Switzerland) · 2024Review
- A review of the impact of social disruptions on food security and food choice.Food science & nutrition · 2024Review
- Antiviral Effects of Pyrroloquinoline Quinone through Redox Catalysis To Prevent Coronavirus Infection.ACS omega · 2023Article
- Xuanfei Baidu decoction in the treatment of coronavirus disease 2019 (COVID-19): Efficacy and potential mechanisms.Heliyon · 2023Review
- The Immunomodulatory Effect of β-Glucan Depends on the Composition of the Gut Microbiota.Foods (Basel, Switzerland) · 2023Article
- Furoquinoline Alkaloids: Insights into Chemistry, Occurrence, and Biological Properties.International journal of molecular sciences · 2023Review
- A Global Overview of Dietary Supplements: Regulation, Market Trends, Usage during the COVID-19 Pandemic, and Health Effects.Nutrients · 2023Review
- The "Vertigo" of the Food Sector within the Triangle of Climate Change, the Post-Pandemic World, and the Russian-Ukrainian War.Foods (Basel, Switzerland) · 2023Article
- Exploring the Amino-Acid Composition, Secondary Structure, and Physicochemical and Functional Properties of Chickpea Protein Isolates.ACS omega · 2023Article
- Optimization of Extraction Parameters and Characterization of Tunisian Date Extract: A Scientific Approach Toward Their Utilization.Sugar tech : an international journal of sugar crops & related industries · 2023Article
- A Real-World Scenario of Citizens' Motivation and Engagement in Urban Waste Management Through a Mobile Application and Smart City Technology.Circular economy and sustainability · 2023Article
- Article
- Deep learning application detecting SARS-CoV-2 key enzymes inhibitors.Cluster computing · 2023Article
15 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As media reports have noted, the COVID-19 pandemic has accelerated market mainstreaming of immune-boosting food bioactives, supplements, and nutraceuticals. However, most studies reporting on the potential of bioactives against COVID-19 transmission have been uploaded as preprints with little opportunity to revise content for benefit and impact. The current review discusses current best evidence and information underpinning the role of food ingredients and bioactive compounds in supporting immune functions in humans and animals, specifically in the prevention and treatment of COVID-19 disease. Up to now, some evidence from randomized population and clinical trials has suggested that vitamin D levels may be linked to COVID-19 transmission and severity. Numerous theoretical studies have pointed to polyphenols and particularly flavonoids as potential inhibitors of SARS-CoV-2 infection. There is also inconclusive evidence to support the future use of β-glucan to address COVID-19 due in part to variability in immune response arising from heterogeneity in polysaccharide branch and chain length for different sources and the absence of a standardized extraction method. To confirm the promising outcomes and hypotheses for bioactive compounds, more randomized and controlled clinical studies are needed. The results of such studies would have a profound effect on the prospects of food supplements and nutraceuticals as potential prophylaxis against COVID-19 and serve to help consumers to protect themselves during the post-lockdown recovery era.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.