Evidence map›Paper›PMID 33233554›Full record

ArticleInternational journal of molecular sciences2020

Responses of DNA Mismatch Repair Proteins to a Stable G-Quadruplex Embedded into a DNA Duplex Structure.

Anzhela V Pavlova, Mayya V Monakhova, Anna M Ogloblina, Natalia A Andreeva, Gennady Yu Laptev, Vladimir I Polshakov, Elizaveta S Gromova, Maria I Zvereva, Marianna G Yakubovskaya, Tatiana S Oretskaya and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Crosstalk between G-Quadruplexes and Dnmt3a-Mediated Methylation of theInternational journal of molecular sciences · 2023
    Article
  5. Review
  6. Article
  7. Review
  8. International journal of molecular sciences · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. The Relevance of G-Quadruplexes for DNA Repair.International journal of molecular sciences · 2021
    Review
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Anzhela V PavlovaDepartment of Chemistry, Lomonosov Moscow State University, Leninskie Gory 1, 119991 Moscow, Russia.ORCID 0000-0002-5961-2277
Mayya V MonakhovaBelozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Leninskie Gory 1, 119991 Moscow, Russia.ORCID 0000-0002-2582-6226
Anna M OgloblinaInstitute of Carcinogenesis, N.N. Blokhin NMRCO, Kashirskoe Shosse 24, 115478 Moscow, Russia.
Natalia A AndreevaDepartment of Chemistry, Lomonosov Moscow State University, Leninskie Gory 1, 119991 Moscow, Russia.
Gennady Yu LaptevDepartment of Chemistry, Lomonosov Moscow State University, Leninskie Gory 1, 119991 Moscow, Russia.
Vladimir I PolshakovFaculty of Fundamental Medicine, Lomonosov Moscow State University, Lomonosovsky Avenue 27/1, 119991 Moscow, Russia.ORCID 0000-0002-3216-5737
Elizaveta S GromovaDepartment of Chemistry, Lomonosov Moscow State University, Leninskie Gory 1, 119991 Moscow, Russia.ORCID 0000-0001-9086-7238
Maria I ZverevaDepartment of Chemistry, Lomonosov Moscow State University, Leninskie Gory 1, 119991 Moscow, Russia.
Marianna G YakubovskayaInstitute of Carcinogenesis, N.N. Blokhin NMRCO, Kashirskoe Shosse 24, 115478 Moscow, Russia.
Tatiana S OretskayaBelozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Leninskie Gory 1, 119991 Moscow, Russia.ORCID 0000-0002-2262-117X
Elena A KubarevaBelozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Leninskie Gory 1, 119991 Moscow, Russia.
Nina G DolinnayaDepartment of Chemistry, Lomonosov Moscow State University, Leninskie Gory 1, 119991 Moscow, Russia.ORCID 0000-0003-1780-813X
Lomonosov Moscow State University · RU

Funding

Russian Foundation for Basic Research 18-29-08040Russian Foundation for Basic Research 18-34-00768Russian Science Foundation 19-14-00115
6 · The paper itself

Abstract

DNA mismatch repair (MMR) plays a crucial role in the maintenance of genomic stability. The main MMR protein, MutS, was recently shown to recognize the G-quadruplex (G4) DNA structures, which, along with regulatory functions, have a negative impact on genome integrity. Here, we studied the effect of G4 on the DNA-binding activity of MutS from

Indexed as

DNA Mismatch RepairGenome, BacterialG-QuadruplexesBinding SitesDNA, BacterialDNA Breaks, Double-StrandedEscherichia coliEscherichia coli ProteinsMutL ProteinsMutS DNA Mismatch-Binding ProteinNucleotide MotifsProtein BindingRhodobacter sphaeroidesDNA, BacterialEscherichia coli ProteinsMutL protein, E coliMutL ProteinsMutS DNA Mismatch-Binding ProteinMutS protein, E coliDNA mismatch repairG-quadruplexMutHMutLMutSprotein–DNA binding

Identifiers

PMID33233554
PMCPMC7699706
OpenAlexW3104416279

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.