Evidence map›Paper›PMID 33233510›Full record

Trial reportNutrients2020

Effects of Continuous Intake of Rosemary Extracts on Mental Health in Working Generation Healthy Japanese Men: Post-Hoc Testing of a Randomized Controlled Trial.

Risa Araki, Kazunori Sasaki, Hiroyuki Onda, Syunsuke Nakamura, Masahiro Kassai, Toshiyuki Kaneko, Hiroko Isoda, Koichi Hashimoto

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Rosemary (Iranian journal of basic medical sciences · 2026
    Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Deciphering Neuroprotective Effect ofCurrent drug targets · 2024
    Review
  9. Article
  10. Review
  11. Frontiers in pharmacology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Risa ArakiDepartment of Clinical and Translational Research Methodology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan.
Kazunori SasakiOpen Innovation Laboratory for Food and Medicinal Resource Engineering (Food-Med OIL), AIST-University of Tsukuba, 1-1-1 Higashi, Tsukuba 305-8565, Japan.
Hiroyuki OndaS&B FOODS INC., 38-8 Miyamoto-cho, Itabashi-ku, Tokyo 174-8651, Japan.
Syunsuke NakamuraS&B FOODS INC., 38-8 Miyamoto-cho, Itabashi-ku, Tokyo 174-8651, Japan.
Masahiro KassaiS&B FOODS INC., 38-8 Miyamoto-cho, Itabashi-ku, Tokyo 174-8651, Japan.
Toshiyuki KanekoTokyo Skytree Station Medical Clinic, 3-33-13 Sumida-ku, Tokyo 131-0033, Japan.
Hiroko IsodaR&D Center for Tailor-Made QOL, University of Tsukuba, 1-2 Kasuga, Tsukuba 305-8550, Japan.
Koichi HashimotoDepartment of Clinical and Translational Research Methodology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan.
University of Tsukuba · JPItoham Foods (Japan) · JP

Funding

S&B FOODS INC. -
6 · The paper itself

Abstract

We previously performed a 4 week interventional trial that suggested that continuous intake of rosemary extract improves the mood states, fatigue, and cognitive function of working generation healthy adult Japanese men. However, the severity of depression in participants in our previous study was relatively mild. Therefore, in the present study, a post-hoc analysis of our previous study was conducted, limited to participants whose total mood disturbance (TMD) scores, which indicate greater mood disturbance, were above the median at baseline, to evaluate whether rosemary extract was effective for individuals with poor mental health. Following the intervention, the scores of TMD and "Confusion-Bewilderment" were significantly decreased (both

Indexed as

Health StatusMental HealthAdultAnxietyCognitionFatigueHumansJapanMaleMood DisordersPlant ExtractsRosmarinusPlant Extractsclinical trialcognitive functiondietary interventionfatiguemental healthmood statesrosemary extracts

Identifiers

PMID33233510
PMCPMC7699484
OpenAlexW3103940097

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.