Evidence map›Paper›PMID 33233456›Full record

ArticleCancers2020

Association of Mutation Profiles with Postoperative Survival in Patients with Non-Small Cell Lung Cancer.

Taichiro Goto, Kei Kunimasa, Yosuke Hirotsu, Takahiro Nakagomi, Yujiro Yokoyama, Rumi Higuchi, Sotaro Otake, Toshio Oyama, Kenji Amemiya, Hitoshi Mochizuki and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Taichiro GotoLung Cancer and Respiratory Disease Center, Yamanashi Central Hospital, Yamanashi 400-8506, Japan.ORCID 0000-0002-2560-3639
Kei KunimasaGenome Analysis Center, Yamanashi Central Hospital, Yamanashi 400-8506, Japan.
Yosuke HirotsuGenome Analysis Center, Yamanashi Central Hospital, Yamanashi 400-8506, Japan.ORCID 0000-0002-8002-834X
Takahiro NakagomiLung Cancer and Respiratory Disease Center, Yamanashi Central Hospital, Yamanashi 400-8506, Japan.
Yujiro YokoyamaLung Cancer and Respiratory Disease Center, Yamanashi Central Hospital, Yamanashi 400-8506, Japan.
Rumi HiguchiLung Cancer and Respiratory Disease Center, Yamanashi Central Hospital, Yamanashi 400-8506, Japan.
Sotaro OtakeLung Cancer and Respiratory Disease Center, Yamanashi Central Hospital, Yamanashi 400-8506, Japan.
Toshio OyamaDepartment of Pathology, Yamanashi Central Hospital, Yamanashi 400-8506, Japan.
Kenji AmemiyaGenome Analysis Center, Yamanashi Central Hospital, Yamanashi 400-8506, Japan.
Hitoshi MochizukiGenome Analysis Center, Yamanashi Central Hospital, Yamanashi 400-8506, Japan.ORCID 0000-0002-1145-0969
Masao OmataGenome Analysis Center, Yamanashi Central Hospital, Yamanashi 400-8506, Japan.
Yamanashi Prefectural Central Hospital · JPOsaka International Cancer Institute · JPUniversity of Tokyo Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Findings on mutations, associated with lung cancer, have led to advancements in mutation-based precision medicine. This study aimed to comprehensively and synthetically analyze mutations in lung cancer, based on the next generation sequencing data of surgically removed lung tumors, and identify the mutation-related factors that can affect clinical outcomes. Targeted sequencing was performed on formalin-fixed paraffin-embedded surgical specimens obtained from 172 patients with lung cancer who underwent surgery in our hospital. The clinical and genomic databases of the hospital were combined to determine correlations between clinical factors and mutation profiles in lung cancer. Multivariate analyses of mutation-related factors that may affect the prognosis were also performed. Based on histology,

Indexed as

lung cancermutationnext generation sequencingsurvivalTP53

Identifiers

PMID33233456
PMCPMC7700403
OpenAlexW3107729901

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.