Evidence map›Paper›PMID 33233335›Full record

ReviewJournal of fungi (Basel, Switzerland)2020

Zinc at the Host-Fungus Interface: How to Uptake the Metal?

Lucas Weba Soares, Alexandre Melo Bailão, Célia Maria de Almeida Soares, Mirelle Garcia Silva Bailão

Abstract readReview
In one paragraph

Review in Journal of fungi (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Global Molecular Response ofJournal of fungi (Basel, Switzerland) · 2023
    Article
  6. Article
  7. ZnBiomolecules · 2022
    Article
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lucas Weba SoaresDepartamento de Bioquímica e Biologia Molecular, Instituto de Ciências Biológicas, Universidade Federal de Goiás, Goiânia 74690-900, Goiás, Brazil.
Alexandre Melo BailãoDepartamento de Bioquímica e Biologia Molecular, Instituto de Ciências Biológicas, Universidade Federal de Goiás, Goiânia 74690-900, Goiás, Brazil.
Célia Maria de Almeida SoaresDepartamento de Bioquímica e Biologia Molecular, Instituto de Ciências Biológicas, Universidade Federal de Goiás, Goiânia 74690-900, Goiás, Brazil.ORCID 0000-0001-5378-9840
Mirelle Garcia Silva BailãoDepartamento de Bioquímica e Biologia Molecular, Instituto de Ciências Biológicas, Universidade Federal de Goiás, Goiânia 74690-900, Goiás, Brazil.ORCID 0000-0003-2053-204X

Funding

Fundação de Amparo à Pesquisa do Estado de Goiás/Instituto Nacional de Ciência e Tecnologia de Interação Patógeno-Hospedeiro (FAPEG/INCT-IPH) 201810267000022Fundação de Amparo à Pesquisa do Estado de Goiás/Programa de Apoio a Núcleos de Excelência (FAPEG/PRONEX) 201710267000506
6 · The paper itself

Abstract

Zinc is an essential nutrient for all living organisms. However, firm regulation must be maintained since micronutrients also can be toxic in high concentrations. This notion is reinforced when we look at mechanisms deployed by our immune system, such as the use of chelators or membrane transporters that capture zinc, when threatened with pathogens, like fungi. Pathogenic fungi, on the other hand, also make use of a variety of transporters and specialized zinc captors to survive these changes. In this review, we sought to explain the mechanisms, grounded in experimental analysis and described to date, utilized by pathogenic fungi to maintain optimal zinc levels.

Indexed as

fungal pathogenesiszinc homeostasisZIP transporters

Identifiers

PMID33233335
PMCPMC7711662

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.