Evidence map›Paper›PMID 33233324›Full record

ArticleJournal of clinical medicine2020

Pre-Hospital Management of Critically Ill Patients with SARS-CoV-2 Infection: A Retrospective Multicenter Study.

Pierrick Le Borgne, Mathieu Oberlin, Adrien Bassand, Laure Abensur Vuillaume, Yannick Gottwalles, Marc Noizet, Stéphane Gennai, Florent Baicry, Deborah Jaeger, Nicolas Girerd and 3 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Prevalence, Presentation and Outcomes of Silent Hypoxemia in COVID-19.Clinical medicine insights. Circulatory, respiratory and pulmonary medicine · 2022
    Review
  7. Impact of Air Transport on SpOJournal of clinical medicine · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Pierrick Le BorgneEmergency Department, University Hospital of Strasbourg, 1 Avenue Molière, 67000 Strasbourg, France.ORCID 0000-0001-9141-6439
Mathieu OberlinEmergency Department, University Hospital of Strasbourg, 1 Avenue Molière, 67000 Strasbourg, France.ORCID 0000-0002-3419-5307
Adrien BassandEmergency Department, University Hospital of Nancy, 29 Avenue du Maréchal de Lattre de Tassigny, 54035 Nancy, France.ORCID 0000-0002-3631-9633
Laure Abensur VuillaumeEmergency Department, Regional Hospital of Metz-Thionville, 1, Allée du Château, 57530 Ars-Laquenexy, France.ORCID 0000-0003-2527-8458
Yannick GottwallesEmergency Department, General Hospital of Colmar, 39 Avenue de la Liberté, 68024 Colmar, France.
Marc NoizetEmergency Department, Mulhouse hospital, 20 Avenue du Dr René Laennec, 68100 Mulhouse, France.
Stéphane GennaiEmergency Department, Reims University Hospital, 45 Rue Cognac-Jay, 51100 Reims, France.ORCID 0000-0002-8490-4706
Florent BaicryEmergency Department, University Hospital of Strasbourg, 1 Avenue Molière, 67000 Strasbourg, France.ORCID 0000-0002-0534-0122
Deborah JaegerEmergency Department, University Hospital of Nancy, 29 Avenue du Maréchal de Lattre de Tassigny, 54035 Nancy, France.ORCID 0000-0002-3583-7172
Nicolas GirerdCentre d'Investigations Cliniques-1433, and INSERM U1116, F-CRIN INI-CRCT, Université de Lorraine, 54000 Nancy, France.
François LefebvreDepartment of Public Health, University Hospital of Strasbourg, 1 Place de l'Hôpital, 67000 Strasbourg, France.
Pascal BilbaultEmergency Department, University Hospital of Strasbourg, 1 Avenue Molière, 67000 Strasbourg, France.
Tahar ChouihedEmergency Department, University Hospital of Nancy, 29 Avenue du Maréchal de Lattre de Tassigny, 54035 Nancy, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe COVID-19 outbreak had a major impact on healthcare systems worldwide. Our study aims to describe the characteristics and therapeutic emergency mobile service (EMS) management of patients with vital distress due to COVID-19, their in-hospital care pathway and their in-hospital outcome.

methodsThis retrospective and multicentric study was conducted in the six main centers of the French Greater East region, an area heavily impacted by the pandemic. All patients requiring EMS dispatch and who were admitted straight to the intensive care unit (ICU) were included. Clinical data from their pre-hospital and hospital management were retrieved.

resultsWe included a total of 103 patients (78.6% male, median age 68). In the initial stage, patients were in a critical condition (median oxygen saturation was 72% (60-80%)). In the field, 77.7% (CI 95%: 71.8-88.3%) were intubated. Almost half of our population (45.6%, CI 95%: 37.1-56.9%) had clinical Phenotype 1 (silent hypoxemia), while the remaining half presented Phenotype 2 (acute respiratory failure). In the ICU, a great number had ARDS (77.7%, CI 95% 71.8-88.3% with a PaO

conclusionThe clinical phenotypes appear to be very distinguishable in the pre-hospital field, yet no difference was found in terms of mortality. This leads us to recommend an identical management in the initial phase, despite the two distinct presentations.

Indexed as

acute respiratory distress syndromeCOVID-19critical careintensive care unitphenotypespre-hospital care

Identifiers

PMID33233324
PMCPMC7700636

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.