ArticleJPEN. Journal of parenteral and enteral nutrition2021
Short-Bowel Syndrome: Epidemiology, Hospitalization Trends, In-Hospital Mortality, and Healthcare Utilization.
Article in JPEN. Journal of parenteral and enteral nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 47 citations in OpenAlex.
- Quality of life and healthcare resource utilization among adult patients with short bowel syndrome: A mixed-methods study leveraging an integrated database.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2026Article
- Effectiveness and Safety of Teduglutide Treatment in Adult Patients with Short Bowel Syndrome: A Case Series and Review of Current Evidence.Journal of clinical medicine · 2026Article
- Double-balloon enteroscopy evaluation and surveillance in patients with short bowel syndrome.Therapeutic advances in gastroenterology · 2026Article
- Small Bowel Ischemia Secondary to Splanchnic Venous Thrombosis in a Postpartum Patient-A Case Report.International medical case reports journal · 2026Article
- Global prevalence of short bowel syndrome-associated intestinal failure in adults and children: A targeted literature review and analysis.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2025Review
- A medium-chain fatty acid analogue prevents endotoxin liver injury in a murine model.Scientific reports · 2025Article
- Chronic Intestinal Failure and Short Bowel Syndrome in Adults: Principles and Perspectives for the Portuguese Health System.GE Portuguese journal of gastroenterology · 2025Review
- Distraction Enterogenesis Induces Desert Hedgehog in the Lengthened Murine Colon.Journal of pediatric surgery · 2024Article
- A Multidisciplinary Approach to the Classification and Management of Intestinal Failure: Knowledge in Progress.Diagnostics (Basel, Switzerland) · 2024Review
- Sepsis during short bowel syndrome hospitalizations: Identifying trends, disparities, and clinical outcomes in the United States.World journal of gastrointestinal pathophysiology · 2024Article
- Fat malabsorption in short bowel syndrome: A review of pathophysiology and management.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2024Review
- Parenteral nutrition: a life-saving intervention for 4 months in short bowel syndrome-a case report and review of the literature.Journal of medical case reports · 2024Review
- The real-world analysis of adverse events with teduglutide: a pharmacovigilance study based on the FAERS database.Frontiers in pharmacology · 2024Article
- Clinical challenges of short bowel syndrome and the path forward for organoid-based regenerative medicine.Regenerative therapy · 2023Review
- Early Central Venous Catheter Replacement After Candida in Pediatric Intestinal Failure Patients.JPGN reports · 2023Article
- Real-World Management of High Stool Output in Patients with Short Bowel Syndrome: An International Multicenter Survey.Nutrients · 2023Article
- Inositol hexaphosphate promotes intestinal adaptation in short bowel syndrome via an HDAC3-mediated epigenetic pathway.Food & nutrition research · 2023Article
- Concise review on short bowel syndrome: Etiology, pathophysiology, and management.World journal of clinical cases · 2022Review
- Management of short-bowel syndrome: A survey of unmet educational needs among healthcare providers.JPEN. Journal of parenteral and enteral nutrition · 2022Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
introductionShort-bowel syndrome (SBS) is a common cause of chronic intestinal failure and is associated with increased morbidity, mortality, poor quality of life, and an increased burden on healthcare costs.
methodsWe used the US Nationwide Inpatient Sample database from 2005 to 2014. We identified adult SBS hospitalizations by using a combination of International Classification of Diseases, Ninth Revision, Clinical Modification codes. We studied the demographics of the patients with SBS and analyzed the trends in the number of hospitalizations, in-hospital mortality, and healthcare costs. We also identified the risk factors associated with in-hospital mortality.
resultsA total of 53,040 SBS hospitalizations were identified. We found that SBS-related hospitalizations increased by 55% between 2005 (N = 4037) and 2014 (N = 6265). During this period, the in-hospital mortality decreased from 40 per 1000 to 29 per 1000 hospitalizations, resulting in an overall reduction of 27%. Higher mortality was noted in SBS patients with sepsis (6.7%), liver dysfunction (6.2%), severe malnutrition (6.0%), and metastatic cancer (5.4%). The overall mean length of stay (LOS) for SBS-related hospitalizations was 14.7 days, with a mean hospital cost of $34,130. We noted a steady decrease in the LOS, whereas the cost of care remained relatively stable.
conclusionsThe national burden of SBS-related hospitalizations continues to rise, and the mortality associated with SBS has substantially decreased. Older SBS patients with sepsis, liver dysfunction, severe malnutrition, and metastatic cancer had the highest risk of mortality. Healthcare utilization in SBS remains high. healthcare utilization; hospitalization trend; mortality; research and diseases; short-bowel syndrome.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.