Evidence map›Paper›PMID 33232795›Full record

ArticleExperimental gerontology2021

Cognitive decline negatively impacts physical function.

Michelle Gray, Joshua L Gills, Jordan M Glenn, Jennifer L Vincenzo, Christopher S Walter, Erica N Madero, Aidan Hall, Nami Fuseya, Nick T Bott

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental gerontology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  15. The association of the comorbidity status of metabolic syndrome and cognitive dysfunction with health-related quality of life.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Michelle GrayExercise Science Research Center, Department of Health, Human Performance, and Recreation, University of Arkansas, USA. Electronic address: rgray@uark.edu.
Joshua L GillsExercise Science Research Center, Department of Health, Human Performance, and Recreation, University of Arkansas, USA.
Jordan M GlennExercise Science Research Center, Department of Health, Human Performance, and Recreation, University of Arkansas, USA; Neurotrack Technologies, Inc., USA.
Jennifer L VincenzoDepartment of Physical Therapy, University of Arkansas for Medical Sciences, USA.
Christopher S WalterDepartment of Physical Therapy, University of Arkansas for Medical Sciences, USA.
Erica N MaderoNeurotrack Technologies, Inc., USA.
Aidan HallNeurotrack Technologies, Inc., USA.
Nami FuseyaNeurotrack Technologies, Inc., USA.
Nick T BottClinical Excellence Research Center, Stanford University School of Medicine, Stanford, CA 94305, USA.

Funding

Expanding Translational Research in ArkansasUL1TR003107 · NCATS · UNIV OF ARKANSAS FOR MED SCIS · PI JAMES, LAURA P · 2019 to 2023
$21.6M
Institutional Career DevelopmentKL2TR003108 · NCATS · UNIV OF ARKANSAS FOR MED SCIS · PI ARTHUR, JOHN M., BORSHEIM, ELISABET · 2019 to 2023
$2.3M
NCATS NIH HHS KL2 TR003108NCATS NIH HHS UL1 TR003107
6 · The paper itself

Abstract

Many older adults report difficulty performing one or more activities of daily living. These difficulties may be attributed to cognitive decline and as a result, measuring cognitive status among aging adults may help provide an understanding of current functional status. The purpose of the present investigation was to determine the association between cognitive status and measures of physical functioning. Seventy-six older adults participated in this study; 41 were categorized as normal memory function (NM) and 35 were poor memory function (PM). NM participants had significantly higher physical function as measured by Short Physical Performance Battery (SPPB; 9.4 ± 2.2 vs. 8.4 ± 2.0; p = .03) and peak velocity (0.67 ± 0.16 vs. 0.56 ± 0.19; p = .04) during a quick sit-to-stand task. Dual-task walking velocities were 22% and 126% slower between cognitive groups for the fast and habitual trials, respectively when compared to the single-task walking condition. Significant correlations existed between measures of memory and physical function. The largest correlations with memory were for peak (r = 0.42) and average (r = 0.38) velocity. The results suggest a positive relationship between physical function and cognitive status. However, further research is needed to determine the mechanism of the underlying relationships between physical and cognitive function.

Indexed as

Activities of Daily LivingCognitive DysfunctionAgedAgingCognitionHumansWalkingAgingCognition, movement velocity, dual-task, memoryPhysical function

Identifiers

PMID33232795
PMCPMC9134126

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.