Evidence map›Paper›PMID 33232574›Full record

ReviewESC heart failure2021

Extracorporeal life support as bridge to recovery in yew poisoning: case reports and literature review.

Julia Hermes-Laufer, Martin Meyer, Alain Rudiger, Julian Henze, Kai Enselmann, Hugo Kupferschmidt, Daniel Müller, Aline Herzog, Dominique Bettex, Dagmar I Keller and 2 more

Open access · goldAbstract readCase ReportsReview
PubMed Full text at PMC Publisher
In one paragraph

Review in ESC heart failure, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

  1. [Severe intoxication after yew (Taxus) ingestion-case report and literature review].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2025
    Review
  2. Article
  3. Article
  4. Review
  5. Poisoning by Plants.Deutsches Arzteblatt international · 2022
    Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Julia Hermes-LauferInstitute of Intensive Care Medicine, University Hospital Zurich, Zurich, Switzerland.
Martin MeyerDepartment of Cardiology, University Heart Center, University Hospital Zurich, Zurich, Switzerland.
Alain RudigerInstitute of Anaesthesiology, University Hospital Zurich, Zurich, Switzerland.
Julian HenzeEmergency Department, University Hospital Zurich, Zurich, Switzerland.
Kai EnselmannEmergency Department, University Hospital Zurich, Zurich, Switzerland.
Hugo KupferschmidtNational Poisons Information Centre, Tox Info Suisse, Associated Institute of the University of Zurich, Zurich, Switzerland.
Daniel MüllerInstitute of Clinical Chemistry, University Hospital Zurich, Zurich, Switzerland.
Aline HerzogEmergency Department, University Hospital Zurich, Zurich, Switzerland.
Dominique BettexInstitute of Anaesthesiology, University Hospital Zurich, Zurich, Switzerland.
Dagmar I KellerEmergency Department, University Hospital Zurich, Zurich, Switzerland.
Bernard KrügerInstitute of Anaesthesiology, University Hospital Zurich, Zurich, Switzerland.ORCID 0000-0002-1148-4376
Judith EngelerEmergency Department, University Hospital Zurich, Zurich, Switzerland.
University Hospital of Zurich · CHUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThis short communication aims to review the treatment of cardiogenic shock in patients with yew poisoning based on two case reports from our institution, focusing on the use of extracorporeal life support (ECLS). METHODS AND

resultsWe report two cases of Taxus baccata poisoning treated with ECLS at our institution and review the literature based on a search in PubMed and Google Scholar on the topic of yew poisoning and ECLS. All cases were combined for analysis of demographics, ECLS therapy, and outcome. Case 1: A 35-year-old woman developed polymorphic ventricular tachycardia followed by cardiovascular arrest 5 h after orally ingesting a handful of yew needles. Successful resuscitation required ECLS for 72 h due to ongoing cardiac arrhythmias and cardiogenic shock. The patient left the hospital without neurological sequelae after 10 days. Case 2: A 30-year-old woman developed refractory cardiac arrhythmias and circulatory arrest. Resuscitation included ECLS for 71 h. T. baccata needles found by gastroscopy confirmed the diagnosis. The patient had no neurologic deficits and was transferred to psychiatry after 11 days. REVIEW OF THE LITERATURE: Nine case reports were found and analysed along with our two cases. Five out of the 11 (45%) patients were female. Median (range) age was 28 (19-46) years. T. baccata needles were ingested with a suicidal intention in all patients. Median (range) duration of ECLS was 70 h (24-120 h). Eight (73%) patients had full neurological recovery.

conclusionsYew poisoning is a differential diagnosis in young psychiatric patients presenting with polymorphic ventricular tachycardia and cardiogenic shock. A characteristic cardiac contraction pattern in echocardiography may present a diagnostic clue. The early use of ECLS is a valuable bridge to recovery in most of these patients.

Indexed as

Extracorporeal Membrane OxygenationPlant PoisoningAdultArrhythmias, CardiacFemaleHumansMiddle AgedShock, CardiogenicTreatment OutcomeCardiogenic shockECLSRefractory ventricular tachycardiaTaxus baccataYew poisoning

Identifiers

PMID33232574
PMCPMC7835583
OpenAlexW3108529475

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.