Evidence map›Paper›PMID 33232547›Full record

ArticleLiver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society2021

Introducing EL-FIT (Exercise and Liver FITness): A Smartphone App to Prehabilitate and Monitor Liver Transplant Candidates.

Andrés Duarte-Rojo, Pamela M Bloomer, Renee J Rogers, Mohamed A Hassan, Michael A Dunn, Amit D Tevar, Samantha L Vivis, Ramon Bataller, Christopher B Hughes, Arny A Ferrando and 2 more

Open access · greenAbstract read
In one paragraph

Article in Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.

  1. Guideline
  2. Trial
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Article
  9. The Role of Exercise in Steatotic Liver Diseases: An Updated Perspective.Liver international : official journal of the International Association for the Study of the Liver · 2025
    Review
  10. Telemedicine in the tertiary liver unit: A feasibility study.Clinical and experimental hepatology · 2024
    Article
  11. Frailty in liver transplantation: Exploring prescribing exercise as medicine to improve patient outcomes.Liver international : official journal of the International Association for the Study of the Liver · 2024
    Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. European Society of Organ Transplantation (ESOT) Consensus Statement on Prehabilitation for Solid Organ Transplantation Candidates.Transplant international : official journal of the European Society for Organ Transplantation · 2023
    Review
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Andrés Duarte-RojoDivision of Gastroenterology, Hepatology and Nutrition Thomas E. Starzl Transplantation Institute, Pittsburgh Liver Research Center, University of Pittsburgh School of Medicine Pittsburgh PA Liver Transplantation Program University of Pittsburgh Medical Center Pittsburgh PA Healthy Lifestyle Institute University of Pittsburgh School of Education Pittsburgh PA Department of Surgery, Thomas E. Starzl Transplantation Institute University of Pittsburgh School of Medicine Pittsburgh PA Donald W. Reynolds Institute on Aging University of Arkansas for Medical Sciences Little Rock AR Division of Gastroenterology and Hepatology Stanford University Palo Alto CA.
Pamela M Bloomer
Renee J Rogers
Mohamed A Hassan
Michael A Dunn
Amit D Tevar
Samantha L Vivis
Ramon Bataller
Christopher B Hughes
Arny A Ferrando
John M Jakicic
W Ray Kim
University of Pittsburgh · USInstitute on Aging · USStanford University · USUniversity of Pittsburgh Medical Center · US

Funding

Pittsburgh Liver Research CenterP30DK120531 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Shuchang Silvia Liu · 2019 to 2026
$10.9M
NIDDK NIH HHS P30 DK120531
6 · The paper itself

Abstract

Preserved physical function is key for successful liver transplantation (LT); however, prehabilitation strategies are underdeveloped. We created a smartphone application (app), EL-FIT (Exercise and Liver FITness), to facilitate exercise training in end-stage liver disease (ESLD). In this feasibility study, we tested EL-FIT app usage and the accuracy of physical activity data transfer and obtained feedback from initial users. A total of 28 participants used the EL-FIT app and wore a physical activity tracker for 38 ± 12 days (age, 60 ± 8 years; 57% males; Model for End-Stage Liver Disease-sodium, 19 ± 5). There was fidelity in data transfer from the tracker to the EL-FIT app. Participants were sedentary (1957 [interquartile range, 873-4643] steps/day) at baseline. Level of training assigned by the EL-FIT app agreed with that from a physical therapist in 89% of cases. Participants interacted with all app features (videos, perceived exertion, and gamification/motivational features). We rearranged training data to generate heart rate-validated steps as a marker of performance and showed that 35% of the participants had significant increases in their physical performance. Participants emphasized their interest in having choices to better engage in exercise, and they appreciated the sense of community the EL-FIT app generated. We showed that patients with ESLD are able to use and interact with the EL-FIT app. This novel smartphone app has the potential of becoming an invaluable tool for home-based prehabilitation in LT candidates.

Indexed as

End Stage Liver DiseaseLiver TransplantationMobile ApplicationsAgedExerciseFemaleHumansMaleMiddle AgedSeverity of Illness IndexSmartphone

Identifiers

PMID33232547
PMCPMC10251157
OpenAlexW3109634296

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.