Evidence map›Paper›PMID 33232474›Full record

ArticleBlood advances2020

A risk score for predicting hospitalization for community-acquired pneumonia in ITP using nationally representative data.

Ye-Jun Wu, Ming Hou, Hui-Xin Liu, Jun Peng, Liang-Ming Ma, Lin-Hua Yang, Ru Feng, Hui Liu, Yi Liu, Jia Feng and 20 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Blood advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

30 authors at 14 institutions in 1 country.

Ye-Jun WuPeking University People's Hospital, Peking University Institute of Hematology, Beijing, China.
Ming HouDepartment of Hematology, Qilu Hospital, Shandong University, Jinan, China.
Hui-Xin LiuDepartment of Clinical Epidemiology and Biostatistics, Peking University People's Hospital, Beijing, China.
Jun PengDepartment of Hematology, Qilu Hospital, Shandong University, Jinan, China.
Liang-Ming MaAffiliated Shanxi Big Hospital of Shanxi Medical University, Taiyuan, China.
Lin-Hua YangDepartment of Hematology, Second Affiliated Hospital of Shanxi Medical University, Taiyuan, China.
Ru FengDepartment of Hematology, Beijing Hospital, Ministry of Health, Beijing, China.
Hui LiuDepartment of Hematology, Beijing Hospital, Ministry of Health, Beijing, China.
Yi LiuDepartment of Geriatric Hematology, Chinese PLA General Hospital, Beijing, China.
Jia FengDepartment of Hematology, Peking University Shenzhen Hospital, Shenzhen, China.
Hong-Yu ZhangDepartment of Hematology, Peking University Shenzhen Hospital, Shenzhen, China.
Ze-Ping ZhouDepartment of Hematology, The Second Affiliated Hospital of Kunming Medical University, Kunming, China.
Wen-Sheng WangDepartment of Hematology, Peking University First Hospital, Beijing, China.
Xu-Liang ShenDepartment of Hematology, Heping Hospital Affiliated to Changzhi Medical College, Changzhi, China.
Peng ZhaoPeking University People's Hospital, Peking University Institute of Hematology, Beijing, China.
Hai-Xia FuPeking University People's Hospital, Peking University Institute of Hematology, Beijing, China.
Qiao-Zhu ZengPeking University People's Hospital, Peking University Institute of Hematology, Beijing, China.
Xing-Lin WangPeking University People's Hospital, Peking University Institute of Hematology, Beijing, China.
Qiu-Sha HuangPeking University People's Hospital, Peking University Institute of Hematology, Beijing, China.
Yun HePeking University People's Hospital, Peking University Institute of Hematology, Beijing, China.
Qian JiangPeking University People's Hospital, Peking University Institute of Hematology, Beijing, China.
Hao JiangPeking University People's Hospital, Peking University Institute of Hematology, Beijing, China.
Jin LuPeking University People's Hospital, Peking University Institute of Hematology, Beijing, China.
Xiang-Yu ZhaoPeking University People's Hospital, Peking University Institute of Hematology, Beijing, China.
Xiao-Su ZhaoPeking University People's Hospital, Peking University Institute of Hematology, Beijing, China.
Ying-Jun ChangPeking University People's Hospital, Peking University Institute of Hematology, Beijing, China.
Lan-Ping XuPeking University People's Hospital, Peking University Institute of Hematology, Beijing, China.
Yue-Ying LiChinese Academy of Sciences Key Laboratory of Genomic and Precision Medicine, Collaborative Innovation Center of Genetics and Development, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China.
Qian-Fei WangChinese Academy of Sciences Key Laboratory of Genomic and Precision Medicine, Collaborative Innovation Center of Genetics and Development, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China.
Xiao-Hui ZhangPeking University People's Hospital, Peking University Institute of Hematology, Beijing, China.
Peking University · CNPeking University People's Hospital · CNNational Clinical Research Center for Digestive Diseases · CNPeking University Shenzhen Hospital · CNQilu Hospital of Shandong University · CNBeijing Hospital · CNBeijing Institute of Genomics · CNChangzhi Medical College · CNChinese PLA General Hospital · CNKunming Medical University · CNPeking University First Hospital · CNSecond Hospital of Shanxi Medical University · CNShanghai Center For Bioinformation Technology · CNShanxi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infection is one of the primary causes of death from immune thrombocytopenia (ITP), and the lungs are the most common site of infection. We identified the factors associated with hospitalization for community-acquired pneumonia (CAP) in nonsplenectomized adults with ITP and established the [corrected] (ACPA) prediction model to predict the incidence of hospitalization for CAP. This was a retrospective study of nonsplenectomized adult patients with ITP from 10 large medical centers in China. The derivation cohort included 145 ITP inpatients with CAP and 1360 inpatients without CAP from 5 medical centers, and the validation cohort included the remaining 63 ITP inpatients with CAP and 526 inpatients without CAP from the other 5 centers. The 4-item ACPA model, which included age, Charlson Comorbidity Index score, initial platelet count, and initial absolute lymphocyte count, was established by multivariable analysis of the derivation cohort. Internal and external validation were conducted to assess the performance of the model. The ACPA model had an area under the curve of 0.853 (95% confidence interval [CI], 0.818-0.889) in the derivation cohort and 0.862 (95% CI, 0.807-0.916) in the validation cohort, which indicated the good discrimination power of the model. Calibration plots showed high agreement between the estimated and observed probabilities. Decision curve analysis indicated that ITP patients could benefit from the clinical application of the ACPA model. To summarize, the ACPA model was developed and validated to predict the occurrence of hospitalization for CAP, which might help identify ITP patients with a high risk of hospitalization for CAP.

Indexed as

PneumoniaPurpura, Thrombocytopenic, IdiopathicAdultChinaHospitalizationHumansRetrospective StudiesRisk Factors

Identifiers

PMID33232474
PMCPMC7686895
OpenAlexW3110122741

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.