ArticlePloS one2020
3 versus 7 Tesla magnetic resonance imaging for parcellations of subcortical brain structures in clinical settings.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Targeting the dopaminergic midbrain with precision 7-Tesla biofeedback training in depression: A proof-of-principle randomized controlled trial.Molecular psychiatry · 2026Article
- Multiscale characterization of the human claustrum from histology to MRI.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- An evaluation of brain volume and cortical thickness measurement at 0.55 T.Magma (New York, N.Y.) · 2026Article
- Delineating In Vivo T1-Weighted Intensity Profiles Within the Human Insula Cortex Using 7-Tesla MRI.Human brain mapping · 2026Article
- Enhancing 7T MRI for deep brain stimulation with deep-learning based image reconstruction and dynamic parallel transmission.NeuroImage. Clinical · 2026Article
- Study protocol for the Champaign-Urbana population study.Frontiers in neuroimaging · 2026Article
- Shared neurobiological changes in individuals with Crohn's disease and major depressive disorder.Communications medicine · 2025Article
- Structural alterations as a predictor of depression - a 7-Tesla MRI-based multidimensional approach.Molecular psychiatry · 2025Article
- Leveraging ultra-high field (7T) MRI in psychiatric research.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Review
- Harnessing the frontal aslant tract's structure to assess its involvement in cognitive functions: new insights from 7-T diffusion imaging.Scientific reports · 2024Article
- Architecture of the subthalamic nucleus.Communications biology · 2024Review
- Ultra-high-field 7T MRI in Parkinson's disease: ready for clinical use?-a narrative review.Quantitative imaging in medicine and surgery · 2023Review
- Is the Brainstem Activation Different Between Healthy Young Male and Female Volunteers at Initiation of Voiding? A High Definition 7-Tesla Magnetic Resonance Imaging Study.International neurourology journal · 2023Article
- Deep Learning Segmentation of the Nucleus Basalis of Meynert on 3T MRI.AJNR. American journal of neuroradiology · 2023Article
- Phenotyping Superagers Using Resting-State fMRI.AJNR. American journal of neuroradiology · 2023Article
- Neuromelanin related ultra-high field signal intensity of the locus coeruleus differs between Parkinson's disease and controls.NeuroImage. Clinical · 2023Article
- Nonparametric 5D D-RJournal of magnetic resonance (San Diego, Calif. : 1997) · 2022Article
- Manual delineation approaches for direct imaging of the subcortex.Brain structure & function · 2022Article
- A probabilistic atlas of the human ventral tegmental area (VTA) based on 7 Tesla MRI data.Brain structure & function · 2021Article
- Utilizing Dynamic Phosphorous-31 Magnetic Resonance Spectroscopy for the Early Detection of Acute Compartment Syndrome: A Pilot Study on Rats.Diagnostics (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
7 Tesla (7T) magnetic resonance imaging holds great promise for improved visualization of the human brain for clinical purposes. To assess whether 7T is superior regarding localization procedures of small brain structures, we compared manual parcellations of the red nucleus, subthalamic nucleus, substantia nigra, globus pallidus interna and externa. These parcellations were created on a commonly used clinical anisotropic clinical 3T with an optimized isotropic (o)3T and standard 7T scan. The clinical 3T MRI scans did not allow delineation of an anatomically plausible structure due to its limited spatial resolution. o3T and 7T parcellations were directly compared. We found that 7T outperformed the o3T MRI as reflected by higher Dice scores, which were used as a measurement of interrater agreement for manual parcellations on quantitative susceptibility maps. This increase in agreement was associated with higher contrast to noise ratios for smaller structures, but not for the larger globus pallidus segments. Additionally, control-analyses were performed to account for potential biases in manual parcellations by assessing semi-automatic parcellations. These results showed a higher consistency for structure volumes for 7T compared to optimized 3T which illustrates the importance of the use of isotropic voxels for 3D visualization of the surgical target area. Together these results indicate that 7T outperforms c3T as well as o3T given the constraints of a clinical setting.
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