Evidence map›Paper›PMID 33232324›Full record

ArticlePLoS neglected tropical diseases2020

Salmonella identified in pigs in Kenya and Malawi reveals the potential for zoonotic transmission in emerging pork markets.

Catherine N Wilson, Caisey V Pulford, James Akoko, Blanca Perez Sepulveda, Alexander V Predeus, Jessica Bevington, Patricia Duncan, Neil Hall, Paul Wigley, Nicholas Feasey and 4 more

Open access · goldAbstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Characteristics of NontyphoidAntibiotics (Basel, Switzerland) · 2024
    Review
  6. Non-typhoidalFrontiers in veterinary science · 2024
    Article
  7. Article
  8. Pathogens (Basel, Switzerland) · 2023
    Review
  9. Review
  10. Invasive non-typhoidalFrontiers in microbiology · 2023
    Article
  11. Frontiers in cell and developmental biology · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Vaccines · 2021
    Article
  17. Article
  18. Genomic Investigation ofFrontiers in microbiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 3 countries.

Catherine N WilsonInstitute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom.ORCID 0000-0002-7150-3081
Caisey V PulfordInstitute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom.ORCID 0000-0003-2500-9119
James AkokoMaseno University, Kisumu, Kenya.
Blanca Perez SepulvedaInstitute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom.ORCID 0000-0002-2891-4010
Alexander V PredeusInstitute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom.ORCID 0000-0002-2750-1599
Jessica BevingtonInstitute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom.ORCID 0000-0002-8434-1368
Patricia DuncanMinistry of Agriculture, Food Security, Irrigation and Water Development, Malawi Government.
Neil HallEarlham Institute, Norwich, United Kingdom.ORCID 0000-0003-2808-0009
Paul WigleyInstitute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom.
Nicholas FeaseyMalawi-Liverpool Wellcome Trust Clinical Research Programme, Blantyre, Malawi.
Gina PinchbeckInstitute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom.
Jay C D HintonInstitute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom.ORCID 0000-0003-2671-6026
Melita A GordonInstitute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom.ORCID 0000-0002-0629-0884
Eric M FèvreInstitute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom.ORCID 0000-0001-8931-4986
University of Liverpool · GBEarlham Institute · GBMalawi Government · MWMaseno University · KE

Funding

Biotechnology and Biological Sciences Research Council BB/L019019/1Medical Research Council G1100783Wellcome TrustWellcome Trust 106914/Z/15/ZWellcome Trust 204822/Z/16/Z
6 · The paper itself

Abstract

Salmonella is a major cause of foodborne disease globally. Pigs can carry and shed non-typhoidal Salmonella (NTS) asymptomatically, representing a significant reservoir for these pathogens. To investigate Salmonella carriage by African domestic pigs, faecal and mesenteric lymph node samples were taken at slaughter in Nairobi, Busia (Kenya) and Chikwawa (Malawi) between October 2016 and May 2017. Selective culture, antisera testing and whole genome sequencing were performed on samples from 647 pigs; the prevalence of NTS carriage was 12.7% in Busia, 9.1% in Nairobi and 24.6% in Chikwawa. Two isolates of S. Typhimurium ST313 were isolated, but were more closely related to ST313 isolates associated with gastroenteritis in the UK than bloodstream infection in Africa. The discovery of porcine NTS carriage in Kenya and Malawi reveals potential for zoonotic transmission of diarrhoeal strains to humans in these countries, but not for transmission of clades specifically associated with invasive NTS disease in Africa.

Indexed as

AnimalsBacterial ZoonosesDrug Resistance, Multiple, BacterialFoodborne DiseasesGastroenteritisHumansKenyaLymph NodesMalawiMicrobial Sensitivity TestsMolecular TypingPork MeatSalmonella Infections, AnimalSalmonella typhimuriumSwineWhole Genome Sequencing

Identifiers

PMID33232324
PMCPMC7748489
OpenAlexW3110134768

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.