Evidence map›Paper›PMID 33232276›Full record

ArticleAging2020

CD36 upregulates DEK transcription and promotes cell migration and invasion via GSK-3β/β-catenin-mediated epithelial-to-mesenchymal transition in gastric cancer.

Jin Wang, Ti Wen, Zhi Li, Xiaofang Che, Libao Gong, Zihan Jiao, Xiujuan Qu, Yunpeng Liu

Erratum issuedAbstract read
In one paragraph

Article in Aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. CD36: The Bridge between Lipids and Tumors.Molecules (Basel, Switzerland) · 2024
    Review
  15. Article
  16. Metabolic heterogeneity in cancer.Nature metabolism · 2024
    Review
  17. Lipid Metabolism as a Potential Target of Liver Cancer.Journal of hepatocellular carcinoma · 2024
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Jin WangDepartment of Medical Oncology, The First Hospital of China Medical University, Shenyang 110001, China.
Ti WenDepartment of Medical Oncology, The First Hospital of China Medical University, Shenyang 110001, China.
Zhi LiDepartment of Medical Oncology, The First Hospital of China Medical University, Shenyang 110001, China.
Xiaofang CheDepartment of Medical Oncology, The First Hospital of China Medical University, Shenyang 110001, China.
Libao GongDepartment of Medical Oncology, The First Hospital of China Medical University, Shenyang 110001, China.
Zihan JiaoDepartment of Medical Oncology, The First Hospital of China Medical University, Shenyang 110001, China.
Xiujuan QuDepartment of Medical Oncology, The First Hospital of China Medical University, Shenyang 110001, China.
Yunpeng LiuDepartment of Medical Oncology, The First Hospital of China Medical University, Shenyang 110001, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evidence indicates that the lipid scavenger receptor CD36 has pro-metastatic functions in several cancers. Although CD36 expression correlates with an unfavorable prognosis in gastric cancer (GC), its specific contribution to disease onset, progression, and/or metastasis remains unclear. Using bioinformatics analyses, we ascertained that CD36 expression was increased in metastatic GC specimens in The Cancer Genome Atlas and Gene Expression Omnibus databases and correlated with poor prognosis. In addition, higher CD36 expression was associated with lymph node metastasis (

Indexed as

beta CateninCarcinomaCD36 AntigensCell Line, TumorCell MovementChromosomal Proteins, Non-HistoneEpithelial-Mesenchymal TransitionFemaleGene Knockdown TechniquesGlycogen Synthase Kinase 3 betaHumansLymphatic MetastasisLymph NodesMaleMiddle AgedNeoplasm Stagingbeta CateninCD36 AntigensCD36 protein, humanChromosomal Proteins, Non-HistoneDEK protein, humanGlycogen Synthase Kinase 3 betaGSK3B protein, humanMYC protein, humanOncogene ProteinsPoly-ADP-Ribose Binding ProteinsProto-Oncogene Proteins c-mycCD36DEKepithelial-to-mesenchymal transitiongastric cancer

Identifiers

PMID33232276
PMCPMC7880392

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.