Evidence map›Paper›PMID 33232223›Full record

ArticleIEEE transactions on bio-medical engineering2021

Extended Signal-Space Separation Method for Improved Interference Suppression in MEG.

Liisa Helle, Jukka Nenonen, Eric Larson, Juha Simola, Lauri Parkkonen, Samu Taulu

Abstract read
In one paragraph

Article in IEEE transactions on bio-medical engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Liisa Helle
Jukka Nenonen
Eric Larson
Juha Simola
Lauri Parkkonen
Samu Taulu

Funding

Scalable Software for Distributed Processing and Visualization of Multi-Site MEG/EEG DatasetsR01NS104585 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI MATTI HAMALAINEN · 2018 to 2026
$4.3M
A Room Temperature Atomic Magnetrode System for Telemetry of Epileptic SeizuresR01NS094604 · NINDS · UNIVERSITY OF COLORADO · PI BARTH, DANIEL S., KNAPPE, SVENJA · 2015 to 2019
$2.5M
NINDS NIH HHS R01 NS094604NINDS NIH HHS R01 NS104585
6 · The paper itself

Abstract

objectiveMagnetoencephalography (MEG) signals typically reflect a mixture of neuromagnetic fields, subject-related artifacts, external interference and sensor noise. Even inside a magnetically shielded room, external interference can be significantly stronger than brain signals. Methods such as signal-space projection (SSP) and signal-space separation (SSS) have been developed to suppress this residual interference, but their performance might not be sufficient in cases of strong interference or when the sources of interference change over time.

methodsHere we suggest a new method, extended signal-space separation (eSSS), which combines a physical model of the magnetic fields (as in SSS) with a statistical description of the interference (as in SSP). We demonstrate the performance of this method via simulations and experimental MEG data.

resultsThe eSSS method clearly outperforms SSS and SSP in interference suppression regardless of the extent of a priori information available on the interference sources. We also show that the method does not cause location or amplitude bias in dipole modeling.

conclusionOur eSSS method provides better data quality than SSP or SSS and can be readily combined with other SSS-based methods, such as spatiotemporal SSS or head movement compensation. Thus, eSSS extends and complements the interference suppression techniques currently available for MEG. SIGNIFICANCE: Due to its ability to suppress external interference to the level of sensor noise, eSSS can facilitate single-trial data analysis, exemplified in automated analysis of epileptic data. Such an enhanced suppression is especially important in environments with large interference fields.

Indexed as

MagnetoencephalographySignal Processing, Computer-AssistedArtifactsBrainBrain Mapping

Identifiers

PMID33232223
PMCPMC8513798

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.