Evidence map›Paper›PMID 33232185›Full record

ArticleExpert review of proteomics2020

Top-down proteomics: challenges, innovations, and applications in basic and clinical research.

Kyle A Brown, Jake A Melby, David S Roberts, Ying Ge

Open access · greenAbstract read
In one paragraph

Article in Expert review of proteomics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed
8.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

78 citing papers in PubMed, 150 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Proteoforms as the true units of physiological function.European journal of applied physiology · 2026
    Review
  8. Article
  9. Precision Profiling of the Cardiovascular Post-Translationally Modified Proteome.Journal of cardiovascular development and disease · 2026
    Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kyle A BrownDepartment of Chemistry, University of Wisconsin-Madison , Madison, Wisconsin, USA.
Jake A MelbyDepartment of Chemistry, University of Wisconsin-Madison , Madison, Wisconsin, USA.ORCID 0000-0003-1499-9508
David S RobertsDepartment of Chemistry, University of Wisconsin-Madison , Madison, Wisconsin, USA.ORCID 0000-0002-0478-4987
Ying GeDepartment of Chemistry, University of Wisconsin-Madison , Madison, Wisconsin, USA.ORCID 0000-0001-5211-6812
University of Wisconsin–Madison · US

Funding

Training Program in Translational Cardiovascular Science (TPTCS)T32HL007936 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI Lee Lochbaum Eckhardt, Gail A Robertson · 2001 to 2026
$11.6M
Deciphering Myofilament Modifications in Ischemic CardiomyopathyR01HL109810 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI GE, YING · 2013 to 2024
$3.5M
Top Down Proteomics Of Myofilaments In Heart FailureR01HL096971 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI GE, YING · 2011 to 2021
$3.3M
Enabling Top-Down Proteomics through Materials Chemistry and NanotechnologyR01GM117058 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI GE, YING, JIN, SONG · 2015 to 2023
$2.7M
Vascular Surgery Research Training ProgramT32HL110853 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI MATSUMURA, JON STEVEN · 2012 to 2021
$2.6M
MASH Explorer, a Comprehensive Software Environment for Top-Down ProteomicsR01GM125085 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI GE, YING · 2018 to 2021
$1.2M
NHLBI NIH HHS R01 HL096971NHLBI NIH HHS R01 HL109810NHLBI NIH HHS T32 HL007936NHLBI NIH HHS T32 HL110853NIGMS NIH HHS R01 GM117058NIGMS NIH HHS R01 GM125085
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Heart DiseasesHumansProtein Processing, Post-TranslationalProteomicsTandem Mass SpectrometryHeart DiseasesMass SpectrometryPost-translational ModificationsProteoformsTop-down Proteomics

Identifiers

PMID33232185
PMCPMC7864889
OpenAlexW3106602244

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.