Evidence map›Paper›PMID 33231918›Full record

ArticleESC heart failure2021

Time-weighted lactate as a predictor of adverse outcome in acute heart failure.

Giorgio Bosso, Valentina Mercurio, Nermin Diab, Antonio Pagano, Giovanni Porta, Enrico Allegorico, Claudia Serra, Giovanna Guiotto, Fabio Giuliano Numis, Carlo Gabriele Tocchetti and 1 more

Open access · goldAbstract read
In one paragraph

Article in ESC heart failure, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 26 citations in OpenAlex.

  1. Impact of matched samples on domain harmonization in cross-cohort NMR metabolomics.Metabolomics : Official journal of the Metabolomic Society · 2026
    Article
  2. Review
  3. Article
  4. Observational
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Giorgio BossoDepartment of Emergency Medicine, Santa Maria delle Grazie Hospital, Pozzuoli, Italy.
Valentina MercurioDepartment of Translational Medical Sciences, Federico II University, Via Sergio Pansini 5, 80131, Naples, Italy.
Nermin DiabDepartment of Respirology, University of Toronto, Toronto, Ontario, Canada.
Antonio PaganoDepartment of Emergency Medicine, Santa Maria delle Grazie Hospital, Pozzuoli, Italy.
Giovanni PortaDepartment of Emergency Medicine, Santa Maria delle Grazie Hospital, Pozzuoli, Italy.
Enrico AllegoricoDepartment of Emergency Medicine, Santa Maria delle Grazie Hospital, Pozzuoli, Italy.
Claudia SerraDepartment of Emergency Medicine, Santa Maria delle Grazie Hospital, Pozzuoli, Italy.
Giovanna GuiottoEmergency Department of San Paolo Hospital, Naples, Italy.
Fabio Giuliano NumisDepartment of Emergency Medicine, Santa Maria delle Grazie Hospital, Pozzuoli, Italy.
Carlo Gabriele TocchettiDepartment of Translational Medical Sciences, Federico II University, Via Sergio Pansini 5, 80131, Naples, Italy.
Fernando SchiraldiEmergency Department of San Paolo Hospital, Naples, Italy.
Ospedale Santa Maria · ITFederico II University Hospital · ITOspedale San Paolo · ITUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe role of dynamic changes in lactate concentrations on prognosis in acute heart failure has been poorly investigated. The aim of this study was to explore the predictive value of 24 h time-weighted lactate (LAC METHODS AND

resultsNinety-six consecutive acute heart failure patients presenting to the Emergency Department of San Paolo Hospital, Naples, Italy, were prospectively enrolled. Arterial blood lactate was measured at admission and during the following 24 h at random time intervals. LAC

conclusionsIn acute heart failure patients, 24 h LAC

Indexed as

Heart FailureLactic AcidHospitalizationHumansIntensive Care UnitsItalyLactic AcidAcute heart failureHospitalizationIntensive carePrognosisTime-weighted lactate

Identifiers

PMID33231918
PMCPMC7835560
OpenAlexW3107771114

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.