Evidence map›Paper›PMID 33231882›Full record

ArticleCancer2021

Results from a prospective longitudinal survey of employment and work outcomes in newly diagnosed cancer patients during and after curative-intent chemotherapy: A Wisconsin Oncology Network study.

Amye J Tevaarwerk, Kris Kwekkeboom, Kevin A Buhr, Alexandra Dennee, William Conkright, Adedayo A Onitilo, Emily Robinson, Harish Ahuja, Roger W Kwong, Ranveer Nanad and 5 more

Abstract read
In one paragraph

Article in Cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Prognostic factors for return to work in breast cancer survivors.The Cochrane database of systematic reviews · 2025
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Unmet needs and problems related to employment and working as reported by survivors with metastatic breast cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  6. Article
  7. Article
  8. Employment disruption among women with gynecologic cancers.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2022
    Article
  9. Survivorship, Version 1.2021.Journal of the National Comprehensive Cancer Network : JNCCN · 2021
    Article
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Amye J TevaarwerkUniversity of Wisconsin Carbone Cancer Center, Madison, Wisconsin.ORCID 0000-0002-8087-5119
Kris KwekkeboomUniversity of Wisconsin Carbone Cancer Center, Madison, Wisconsin.
Kevin A BuhrDivision of Hematology/Oncology & Palliative Care, Department of Medicine, University of Wisconsin, Madison, Wisconsin.
Alexandra DenneeUniversity of Wisconsin Carbone Cancer Center, Madison, Wisconsin.
William ConkrightFox Valley Hematology/Oncology, Appleton, Wisconsin.
Adedayo A OnitiloMarshfield Clinic, Weston, Wisconsin.
Emily RobinsonMercy Health System, Janesville, Wisconsin.
Harish AhujaAspirus Reg Cancer Center, Wausau, Wisconsin.
Roger W KwongGundersen Lutheran Med Center, La Crosse, Wisconsin.
Ranveer NanadColumbia St. Mary's, Milwaukee, Wisconsin.
Douglas A WiegmannDivision of Hematology/Oncology & Palliative Care, Department of Medicine, University of Wisconsin, Madison, Wisconsin.
Karen ChenDepartment of Industrial and Systems Engineering, North Carolina State University, Raleigh, North Carolina.
Noelle K LoConteUniversity of Wisconsin Carbone Cancer Center, Madison, Wisconsin.ORCID 0000-0002-3883-4153
Kari B WisinskiUniversity of Wisconsin Carbone Cancer Center, Madison, Wisconsin.ORCID 0000-0003-3535-0652
Mary E SestoUniversity of Wisconsin Carbone Cancer Center, Madison, Wisconsin.

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Nihal Ahmad · 1985 to 2026
$142.6M
University of Wisconsin Institute for Clinical and Translational ResearchUL1TR002373 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI ELIZABETH S BURNSIDE, Allan R. Brasier · 2017 to 2026
$75.9M
Institutional Clinical and Translational Science AwardUL1TR000427 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$32.2M
Institutional Clinical and Translational Science AwardKL2TR000428 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$6.2M
NCATS NIH HHS KL2 TR000428NCATS NIH HHS UL1 TR000427NCATS NIH HHS UL1 TR002373NCI NIH HHS P30 CA014520
6 · The paper itself

Abstract

backgroundPostcancer work limitations may affect a substantial proportion of patients and contribute to the "financial toxicity" of cancer treatment. The degree and nature of work limitations and employment outcomes are poorly understood for cancer patients, particularly in the immediate period of transition after active treatment. We prospectively examined employment, work ability, and work limitations during and after treatment.

methodsA total of 120 patients receiving curative therapy who were employed prior to their cancer diagnosis and who intended to work during or after end of treatment (EOT) completed surveys at baseline (pretreatment), EOT, and 3, 6, and 12 months after EOT. Surveys included measures of employment, work ability, and work limitations. Descriptive statistics (frequencies, percentages, means with standard deviations) were calculated.

resultsA total of 111 participants completed the baseline survey. On average, participants were 48 years of age and were mostly white (95%) and female (82%) with a diagnosis of breast cancer (69%). Full-time employment decreased during therapy (from 88% to 50%) and returned to near prediagnosis levels by 12-month follow-up (78%). Work-related productivity loss due to health was high during treatment.

conclusionsThis study is the first to report the effects of curative intent cancer therapy on employment, work ability, and work limitations both during and after treatment. Perceived work ability was generally high overall 12 months after EOT, although a minority reported persistent difficulty. A prospective analysis of factors (eg, job type, education, symptoms) most associated with work limitations is underway to assist in identifying at-risk patients.

Indexed as

EmploymentAdultFemaleHumansLongitudinal StudiesMaleMiddle AgedNeoplasmsProspective StudiesSurveys and QuestionnairesWork Capacity Evaluationcancer survivorshipcancer work limitationsreturn to workworking during cancer treatment

Identifiers

PMID33231882
PMCPMC7945680

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.