Trial reportEuropean child & adolescent psychiatry2022
Internet-based guided self-help comprehensive behavioral intervention for tics (ICBIT) for youth with tic disorders: a feasibility and effectiveness study with 6 month-follow-up.
Trial report in European child & adolescent psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04087616 (Internet-based -Guided Self-help Intervention for Children With Chronic Tics Syndrome or Tourette Syndrome), which is not on this map. Cited by 28 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Internet-based -Guided Self-help Intervention for Children With Chronic Tics Syndrome or Tourette Syndrome: Comprehensive Behavioral Intervention for Tics (CBIT) Versus Waiting List: Reduction of Tic Severity and Quality of Life Measures
Who cites it
28 citing papers in PubMed, 3 syntheses or guidelines pooled it, 73 citations in OpenAlex.
- Digital psychological interventions in youth with neurological disorders: a systematic review.Journal of pediatric psychology · 2026Pooled it
- Digital health interventions with healthcare information and self-management resources for young people with ADHD: a mixed-methods systematic review and narrative synthesis.European child & adolescent psychiatry · 2025Pooled it
- European clinical guidelines for Tourette syndrome and other tic disorders-version 2.0. Part II: psychological interventions.European child & adolescent psychiatry · 2022Guideline
- Therapist-guided, mobile app-assisted behavioural treatment for children and adolescents with chronic tic disorders: a pilot randomised controlled trial.European child & adolescent psychiatry · 2026Trial
- Online remote behavioural intervention for tics in 9- to 17-year-olds: the ORBIT RCT with embedded process and economic evaluation.Health technology assessment (Winchester, England) · 2023Trial
- Therapist-Supported Internet-Delivered Exposure and Response Prevention for Children and Adolescents With Tourette Syndrome: A Randomized Clinical Trial.JAMA network open · 2022Trial
- Contemporary Perspectives on Neurobiology and Treatment of Tic Disorders: A Narrative Review.Journal of the Korean Academy of Child and Adolescent Psychiatry · 2026Article
- Digital-Supported Delivery of Behavioural Therapy for Patients with Tic Disorders: A Narrative Review.Brain sciences · 2026Review
- A randomized clinical trial of remote Group-Based comprehensive behavioral intervention for tics.European child & adolescent psychiatry · 2026Article
- Digital health and Tourette Syndrome: new technological frontiers in diagnosis and management.Frontiers in psychiatry · 2026Review
- Effects of a Board Game on Tic Management and Psychosocial Functioning in Adolescents With Tourette Syndrome: Randomized Controlled Trial.JMIR serious games · 2025Article
- Care Delivery Strategies for Anxiety, Depression, Obsessive Compulsive Disorder, and Tourette Syndrome to Improve Health Outcomes in Children and Youth.Child psychiatry and human development · 2025Review
- Meta-anlaysis of Internet-based Behavior Therapy for Tic Disorder.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2025Article
- Integrating behavioral interventions for Tourette's syndrome: Current status and prospective.World journal of psychiatry · 2025Article
- Evidence-Based Behavior Therapy for Tourette Syndrome.The Psychiatric clinics of North America · 2025Review
- Efficacy of therapist-supported online remote behavioral therapy for tic disorders: a systematic review and meta-analysis.Frontiers in psychiatry · 2025Review
- [Advances in the application of comprehensive behavioral intervention in tic disorder].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024Review
- Exposure and response prevention versus risperidone for the treatment of tic disorders: a randomized controlled trial.Frontiers in psychiatry · 2024Article
- Working Mechanisms of Exposure and Response Prevention in the Treatment of Tourette Syndrome and Tic Disorders Revisited: No Evidence for within-Session Habituation to Premonitory Urges.Journal of clinical medicine · 2023Article
- Cognitive and Neural Mechanisms of Behavior Therapy for Tics: A Perception-Action Integration Approach.Biomedicines · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Practice guidelines endorse comprehensive behavioral intervention for tics (CBIT) as first-line treatment for tic disorders (TD) in youth. Nevertheless, CBIT is rarely available due to various barriers. This study evaluated the feasibility and potential effectiveness of an Internet-based, self-help CBIT program (ICBIT) guided by parents with minimal therapist support delivered via telepsychotherapy. Forty-one youths, aged 7-18 years, were randomly assigned to receive either ICBIT (n = 25) or a wait-list (WL) condition (n = 16) in a crossover design. ICBIT was feasible to implement and at post-treatment, 64% of the participants have improved significantly. Results demonstrated clinically meaningful reductions in tic severity and improved youth global impairment and functioning. Gains were maintained over a 6-month follow-up period. The effect size for the primary outcome measure (Yale Global Tic Severity Scale) ranged between large effect size (Cohen"s d = 0.91) at post-intervention to very large effect size (Cohen's d = 2.25) 6 months after the end of the acute intervention. These were comparable to face-to-face delivery treatment trials for TD. Participants rated the intervention as highly acceptable and satisfactory. Youth receiving ICBIT experienced improvement in self-esteem and comorbidity. Finally, during the COVID-19 pandemic, the ICBIT program enabled the delivery of the intervention consecutively without interruption. The results observed provide preliminary evidence of the feasibility and effectiveness of this innovative modality to assist youth with TD and remove various barriers to treatment, including those during a public crisis, such as the COVID-19 pandemic. Larger studies with an active control group are warranted.Trial registration URL: http://clinicaltrials.gov, ClinicalTrials.gov Identifier: NCT04087616.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.