Evidence map›Paper›PMID 33231766›Full record

ArticleIndian journal of gastroenterology : official journal of the Indian Society of Gastroenterology2020

Splenic stiffness and platelet count to predict varices needing treatment in pediatric extrahepatic portal vein obstruction.

Srinivas Srinidhi Vadlapudi, Barath Jagadisan, Ramesh Ananthkrishnan, Sunil Narayanaswamy

Abstract read
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In one paragraph

Article in Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. APSPGHAN Statement on Endoscopic Variceal Bleeding Hemostasis.Pediatric gastroenterology, hepatology & nutrition · 2026
    Review
  5. Coagulation profile and platelet count in pediatric patients with extrahepatic portal vein obstruction.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2025
    Article
  6. Review
  7. Article
  8. Review
  9. Editorial commentary on the Indian Journal of Gastroenterology November-December 2020.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Srinivas Srinidhi VadlapudiDepartment of Pediatrics, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry 605 006, India.
Barath JagadisanDepartment of Pediatrics, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, 605 006, India. barathjag@yahoo.com.ORCID http://orcid.org/0000-0002-2108-9054
Ramesh AnanthkrishnanDepartment of Radiodiagnosis, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, 605 006, India.
Sunil NarayanaswamyDepartment of Radiodiagnosis, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, 605 006, India.
Jawaharlal Institute of Post Graduate Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSurveillance endoscopy to detect varices needing treatment (VNT) is important to prevent bleeding and morbidity in portal hypertension. In adult and pediatric cirrhosis, platelet count and liver stiffness measurement (LSM) are useful in selecting patients for endoscopy. Such recommendations do not exist for extrahepatic portal vein obstruction (EHPVO). Splenic stiffness measurement (SSM) has been studied in adult and pediatric EHPVO with conflicting results and methodological errors. This study evaluates the role of platelet counts and SSM to predict VNT and bleeding in pediatric EHPVO while comparing LSM and SSM between pediatric EHPVO and controls.

methodsOne hundred and seven children (55 with EHPVO and 52 controls) were recruited. Clinical, biochemical, hematological, and radiographic parameters of all children were noted. All children with EHPVO underwent endoscopy.

resultsOf the 55 children with EHPVO, 48 (87.3%) had VNT. There was no difference in the platelet counts (85,000/mm

conclusionSSM is higher in EHPVO bleeders but SSM and platelet counts are unreliable to predict VNT in pediatric EHPVO. Surveillance endoscopies may be needed in all pediatric EHPVO until better screening strategies are available.

trial registrationNot applicable.

Indexed as

ElasticityPlatelet CountChildConstriction, PathologicEndoscopy, GastrointestinalEsophageal and Gastric VaricesFemaleGastrointestinal HemorrhageHumansHypertension, PortalMalePortal VeinSpleenAcoustic radiation force impulseBleedingExtrahepatic portal vein obstructionLiver stiffnessPlatelet countSplenic stiffnessSurveillance endoscopyVarices needing treatment

Identifiers

PMID33231766
OpenAlexW3107775143

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.